Ch. 3 Embryology Flashcards
Embryology
Development of the embryo
When does ovulation occur?
14th day of menstrual cycle
When does fertilization occur?
12-24 hours after ovulation
Where does fertilization occur?
In the Fallopian tube or oviduct
Gametes are….
Haploid (n) cells… only 23 chromosomes
Occur during meiosis
Sperm and oocyte cells
What is the pre-embryonic development order?
1st two weeks of development
- Zygote
- Cleavage
- Morula
- Blastocyst
- Implantation
Zygote
Memborous layer - Zona Pellucida
Single Diploid (2n) Cell- half from each side
23 pairs of chromosomes
Divides once it reaches 2 cell stage
Cleavage
Early mitotic sequence
First Division: 12-16 hours after fertilization
One cell becomes two
Does not increase in size
Morula
Solid ball of more than 12-16 cells
72 hours after fertilization (day 3)
by day 4 —> in uterus and 60 cells
Blastocyst
Days 4-7
a. Deterioration of zona pellucida - fluid begins to leak through (resulting in a blastocyst cavity)
b. Cavity forms
c. Inner cell mass (embryoblast) - rightly packed group of cells located only within one side of the blastocyst
d. trophoblast - outer ring of cells surrounding the fluid filled cavity (forming the chorion)
Implantation
A process where the blastocyst burrows into and embeds within the uterine wall (endometrium)
Begins around day 6 (completed 2nd week)
a. trophoblast cells “invade” wall of the uterus
b. Invading cells (chorion) from finger like processes around blood vessels in the uterus
c. chorion cells produce HCG
d. Uterine tissue grows in response to invading trophoblast
Chorion
Invading cells form finger like processes around blood vessels in the uterus
- – Produce HCG
- the outermost extraembryonic membrane –> eventually will form the placenta
Human Chorionic Gonadotrophin
HCG
Maintains production of ovarian hormones
What do ovarian hormones do?
Prevents menstruation & causes uterine growth
trophoblast
outer ring of cells surrounding the fluid filled vacity