ch 27 Flashcards
Mitosis purpose and outcome
- Purpose: Cell division for growth, tissue repair, and asexual reproduction.
- Outcome: Produces two genetically identical diploid daughter cells (same number
Stages of the mitosis
- Prophase: Chromosomes condense, spindle fibers form, and the nuclear envelope breaks down.
- Metaphase: Chromosomes align at the cell’s equatorial plate.
- Anaphase: Sister chromatids separate and move to opposite poles.
- Telophase: Nuclear envelopes reform around each set of chromosomes, which decondense, and the cell begins to divide.
- Cytokinesis: Cytoplasm divides, resulting in two separate cells.
Meiosis purpose and outcome
- Purpose: Production of gametes (sperm and eggs) for sexual reproduction.
- Outcome: Produces four genetically unique haploid cells (half the chromosome number of the original cell).
Stages of the meiosis 1
- Prophase I: Chromosomes pair up in homologous pairs and exchange segments (crossing over), increasing genetic diversity.
- Metaphase I: Homologous chromosome pairs align at the cell equator.
- Anaphase I: Homologous chromosomes (not sister chromatids) are separated to opposite poles.
- Telophase I and Cytokinesis: Two haploid cells form, each with half the number of chromosomes, but each chromosome still consists of two sister chromatids.
Stages of the meiosis 2
- Prophase II: Chromosomes condense again in each haploid cell.
- Metaphase II: Chromosomes align at the equator in both cells.
- Anaphase II: Sister chromatids separate and move to opposite poles.
- Telophase II and Cytokinesis: Results in four genetically unique haploid cells.
Key Differences Between Mitosis and Meiosis
- Chromosome Number: Mitosis maintains the diploid number, while meiosis reduces it to haploid.
- Genetic Variation: Mitosis produces identical cells; meiosis introduces genetic diversity through crossing over and independent assortment.
- Divisions: Mitosis has one division, while meiosis includes two rounds (Meiosis I and Meiosis II).
Oogenesis location
Ovaries in females.
Oogenesis Process:
- Begins before birth: In the fetal stage, oogonia (diploid stem cells) undergo mitosis to form primary oocytes, which begin meiosis I but pause at prophase I.
- After puberty: Each month, one primary oocyte resumes meiosis I in response to hormonal signals. This oocyte divides into two cells—a large secondary oocyte and a smaller first polar body (which typically degenerates).
- Ovulation: The secondary oocyte is released during ovulation. It begins meiosis II but pauses at metaphase II unless fertilization occurs.
- If fertilized: The secondary oocyte completes meiosis II, forming a mature ovum and a second polar body. The mature ovum then combines with sperm to form a zygote.
Spermatogenesis Location
Seminiferous tubules in the testes of males.
Spermatogenesis Process
- Begins at puberty: Spermatogonia (diploid stem cells) divide by mitosis, creating two cell types—Type A cells (maintain the germ line) and Type B cells (develop into sperm).
- Meiosis I: Type B cells (now primary spermatocytes) undergo meiosis I to form two haploid secondary spermatocytes.
- Meiosis II: Each secondary spermatocyte quickly undergoes meiosis II, resulting in four haploid spermatids.
- Spermiogenesis: Spermatids undergo further maturation, developing a flagellum, acrosome (enzyme cap), and losing excess cytoplasm to become fully formed spermatozoa (sperm).
* End Result: Four functional sperm cells per spermatogonium, optimized for mobility and fertilization.
Key Differences of oogenesis and spermatogenesis
- Timing: Oogenesis largely completes in the fetal period with pauses, while spermatogenesis is a continuous process from puberty onward.
- Output: Oogenesis produces one egg with ample cytoplasm per cycle; spermatogenesis produces four motile sperm per cycle.
Gonadotropin-Releasing Hormone (GnRH):
o Secreted by the hypothalamus.
o Stimulates the anterior pituitary gland to release FSH and LH.
Follicle-Stimulating Hormone (FSH):
o Released by the anterior pituitary.
o Stimulates the growth and maturation of ovarian follicles in the ovaries.
o Supports granulosa cells in the follicles to produce estrogen.
Luteinizing Hormone (LH):
o Also released by the anterior pituitary.
o Triggers ovulation by causing the mature follicle to release the secondary oocyte.
o LH surge leads to the formation of the corpus luteum, which produces progesterone.
Estrogen
o Produced by granulosa cells in the follicles.
o Regulates the development of the female reproductive system, secondary sexual characteristics, and helps prepare the endometrium for potential implantation.
o High levels trigger the LH surge.
Progesterone:
o Secreted mainly by the corpus luteum after ovulation.
o Maintains the endometrial lining of the uterus, essential for supporting early pregnancy.
o Inhibits further release of FSH and LH during the luteal phase.
Inhibin
o Secreted by the granulosa cells.
o Inhibits FSH release, preventing the maturation of additional follicles during the cycle.
Testes
o Male gonads located in the scrotum.
o Produce sperm through spermatogenesis and secrete testosterone.