CH 22. Corneal Deposits Flashcards
Where are the cornea verticillata deposits located?
Within the epithelium.
Name conditions associated to cornea verticillata.
- Fabry’s disese
- Amiodarone
- Cloroquine
- Quinacrine
- Clorpromazine
- Indometacin
- Clofazimine
- Suramin
- Naproxen
- Tilorone
Name this finding
Cornea Verticillata
Name this finding
Striate Melanokeratosis
What is Striate Melanokeratosis
It is a normal finding in pigmented individuals or a response to trauma or inflamation in lighter pigmented individuals, it represents a migration of pigmented limbal stem cells.
Name the different epithelial iron lines
- Palpebral fissure: Hudson Stahli
- Head of a pterygium: Fleischer
- Head of a filtering bleb: Ferry
- Adjacent to salzmann or other focal elevations
- Anterior to sutures of keratoplasty: Mannis
- After keratorefractive surgery
Name this condition and describe where are the deposits located.
Spheroidal degeneration
Deposits are located withind the bowman’s layer and anterior corneal stroma.
In primary form, They can initially be located in nasal and temporal corneal, since there is a correlation with UV radiation exposure
In the secondary form, it is associated to an area of cronic inflamation and vascularization.
Name this finding and the situation it is associated to?
Adrenochrome deposits
It is associated to topical epinephrine use for glaucoma.
Name this condition
Subepithelial mucinous dystrophy
What gives the cornea with band keratopathy its “Zwiss Cheese appearance”
Calcium is deposited relatevely homogenously in the epithelium, bowman and anterior stroma, but small areas are spared where corneal nerves cross the bowman’s.
What is the most likely diagnosis for this image?
subepithelial quinolone deposits.
This deposits can accumulate after the use of topical cipro/norfloxacine on an <strong>open epithelial defect</strong>.
If this patient is a chronic contact lens user, what is the most likely diagnosis for this finding?
Mucin Balls
Given that the deposits presented in the image are intraepithelial, what is the most likely diagnosis?
Meesman Corneal Dystrophy
What is the most likely diagnosis, and what is the substance that is deposited?
Gelatinous Drop-Like Dystrophy
Inheritance and afected enzime in tyrosinemia II
AD
Tyrosine Aminotransferase
Given that the follonwing lesions doesnt stain with dyes, what is the most likely diagnosis?
Linear and branching epithelial and subepithelial deposits that resemble herpetic keratitis, but that does not stain whith dyes:
Must Rule out Tyrosinemia II
Given that this globular lesions are located within under the epithelium, what is the most likely diagnosis?
Intraepithelial ointment Globules
ophthalmic ointment preparations can become entrapped in the epithelium after corneal abrasions have healed
Can a corneal opacity due to blood staining clear?
Yes, but in severe staining it can last for years, and clearing starts in the periphery which means that the central cornea can remain damaged for a very long period.
What is the most likely diagnosis:
Granular corneal dystrophy
Given that this patient has a bilateral, chronic condition, what is the most likely diagnosis?
Corneal Macular Distrophy
What is the most likely diagnosis given that this lesions are stromal, central, bilateral and asociated to corneal erosions?
Lattice Corneal Distrophy
Where can the crystals be found in Bietti`s corneal dystrophy?
Cornea a Retina.
Biettis corneal dystrophy presentation?
3rd decade, with nyctalopia, poor dark adaptation, peripheral visual field loss, and central visual acuity loss.
What percentage of patients with Wilson´s Disease have a Copper Ring?
KF ring is present in 95% of these patients.
Because of its peripheral location (at the schwalbe´s line) it may be imposible to see it without gonioscopy at early stages
Name this finding
Chysiasis
Given that this is a chronic contact lens user, name this finding.
Motted Cyan Corneal Staining
What is the correct term for corneal copper deposition.
Corneal Chalcosis.
Given that this patient has these Farinata-like deposits in the posterior stroma, inmediately anterior to de descemet membrane. What is the diagnosis?
Predescemet´s corneal distrophy.
This patien has been using an eyelash dye, she now consults for gleyish discoloration of the conjuntiva, cornea appears as shown. What is the diagnosis?
Corneal Argyrosis.
