Ch. 20 - Microbial Diseases of CNS and Eyes Part 2 Flashcards

1
Q

Leprosy aka?

A

Hansen’s disease

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2
Q

Death from leprosy is ___?

A

rare

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3
Q

Which leprosy is non-progressive and involves loss of sensation of skin?

A

Tuberculoid leprosy

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4
Q

Which leprosy is progressive, gradual loss of facial features, etc. Development is ____ and may take ___?

A

lepromatous leprosy
Very slow
years

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5
Q

Strong immune system = which type of leprosy?

A

Tuberculoid leprosy

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6
Q

Weaker immune system = which type of leprosy?

A

Lepromatous leprosy

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7
Q

What causes leprosy?

A

Mycobacterium leprae

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8
Q

What type of pathogen is mycobacterium leprae?

A

Bacteria (acid-fast)

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9
Q

Botulism is caused by ?

A

Clostridium botulinum

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10
Q

What type of pathogen is clostridium botulinum?

A

Bacteria (gram +)

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11
Q

Botulism causes what type of paralysis?

A

flaccid

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12
Q

Botulism causes death by

A

Asphyxiation - cannot inhale

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13
Q

Contaminated food (esp. Home canned), preserved fish, honey (infants), and endospore entering wounds are modes of transmission for which bacteria?

A

Clostridium botulism

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14
Q

Botulism in babies is called?

A

Floppy baby syndrome

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15
Q

Botulism is what type of threat?

A

Category A bioterrorist threat

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16
Q

What is the most common form of botulism in the US?

A

Infantile botulism

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17
Q

Is botulism extremely potent?

A

YES

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18
Q

Severe muscular contraction; lock jaw, sweating, drooling, grouchiness, constant back spasms are symptoms of what?

A

tetanus

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19
Q

Tetanus aka?

A

lockjaw

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20
Q

Tetanus caused by?

A

Clostridium tetani

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21
Q

Death from tetanus is by?

A

Asphyxiation - cannot exhale

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22
Q

Break in skin, mucus membrane; puncture wounds’ umbilical stump are modes of transmission for what disease?

A

tetanus

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23
Q

Clostridium tetani is what type of pathogen?

A

Bacteria (gram +)

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24
Q

Smiling spasm is called?

A

Rises sardonicus

25
Neonatal tetanus mortality is?
>90%
26
The mortality with neonatal tetanus is caused by what?
Infected umbilical stump
27
Viral meningitis aka?
Aseptic meningitis
28
What type of pathogen is viral meningitis?
RNA virus
29
Which is more common than bacterial, fungal, or viral meningitis?
viral
30
Mode of transmission for viral meningitis is?
Feces and respiratory droplets
31
What causes viral meningitis?
enterovirus genus (90% of cases)
32
What can also cause leprosy that is also strange?
Handling or consuming armadillos.
33
What are the three forms of botulism?
foodborne, infant, and wound
34
Mode of transmission for infant botulism?
Ingestion of endospores - esp. Honey or corn syrup
35
Wound botulism has similar signs and symptoms except:
NO GI system involvement
36
What do they administer to treat botulism?
antitoxin
37
What is the earliest sign of tetanus?
lockjaw
38
Clostridium tetani produces a neurotoxin called?
tetanospasmin
39
Tetanus is often associated with what? Is it cause by this?
Rust | NO
40
Highest mortality rate are for _______ people and people _____?
Unvaccinated | Over 60 years of age
41
What is a passive immunotherapy administered for tetanus?
antitoxin
42
What is an active immunization administered for tetanus?
Tetanus toxoid
43
Paralytic polio can result in _______. (directly infects nerve cells)
bulbar poliomyelitis
44
Who developed the inactivated polio vaccine (IPV)?
Jonas Salk
45
Who developed the oral (live) polio vaccine?
Albert Sabin
46
Polio remains endemic in only three coutries:
Nigeria, Pakistan, and Afghanistan
47
Is there a cure for polio?
no
48
Hydrophobia (sensitivity to H2O) is a neurological manifestation of what disease?
rabies
49
Negro bodies are a histology for what disease?
rabies
50
What is the vaccine for rabies?
Human diploid cell vaccine (HDCV)
51
When do arboviruses cause encephalitis?
When they cross the blood brain barrier
52
If arbovirus does not cross BBB, what are the symptoms?
Mild, coldlike symptoms
53
EEE fatality is ___?
30-35%
54
WEE fatality is ___?
low
55
West Nile encephalitis virus is a _____ endemic.
seasonal
56
People can get Tick-borne encephalitis by Ixodes ticks and what else?
Drinking unpasteurized milk
57
Fungal infections of the CNS spread to CNS from where? Via what?
Lungs | blood
58
Tick borne encephalitis was primarily studied in what country?
Russia
59
Meningitis most severe to least severe.
Bacterial, fungal, viral