ch 2 getting energy from energy Flashcards
krebs cycle
also known as the
citric acid cycle
krebs cycle
this series of energy-producing chemical reactions begins in the
mitochondria after pyruvate arrives
krebs cycle
before the krebs cycle can begin
- the pyruvate loses a carbon dioxide group to form acetyl coenzyme A (acetyl CoA)
- the acetyl CoA combines with a four-carbon molecule (oxaloacetic acid or OAA) to form a six-carbon citric acid molecule that then enters the krebs cycle
- the CoA is released intact to bind with another acetyl group reforming the acetyle CoA to be used with the next pyruvate
krebs cycle
the krebs cycle goes through eight steps rearranging the atoms of citric acid to produce different intermediate molecules called
keto acids
krebs cycle
after producing keto acids this generates
1 ATP (for each pyruvate) and four energy molecules (3 NADH and 1 FADH2) which power the electron transport chain
krebs cycle
in the final step of the krebs cycle
OAA is regenerated to get to the next cycle going and the carbon dioxide produced during this cycle is released from the cell to be exhaled from the lungs
electron transport chain
the electron transport chain which requires
- oxygen
- the final step of cellular respiration
- generates the bulk of the ATP
electron transport chain
the chain itself is a series of
enzyme complexes aligned on the inner folds of the mitochondria
electron transport chain
electrons from the energy molecules NADH and FADH2 are passed into the
chain and bounced from one protein to the next much like a game of hot potato
electron transport chain
at the end of the chain a molecule of H2O is created and the energy from the bouncing electrons power
- oxidative phosphorylation–where an enzyme called ATP synthase reattaches a phosphate group to ADP creating ATP
- for every glucose molecule metabolized 34 molecules of ATP are generated by the electron transport chain
one last thing the severe sorness and fatigue you feel in your muscles after strenous exercise is the result of lactic acid buildup during
anaerobic respiration
but glycolysis does need a steady supply of
NADH+ which usually comes from the oxygen-dependent electron transport chain
in the absence of NADH+ the body begins a process called
- lactic acid fermentation
- in which one molecule of pyruvate combines with one molecule of NADH to produce ATP, a molcule of NAD+,plus a molcule of the toxic byproduct lactic acid
while useful for energy creation in musles when O2 has been used up it hardly seems worth it–anaerobic respiration provides only
2 ATP molecules per glucose compared to the 38 of aerobic respiration
tack on the creation of lactic acid which causes
- muscle fatigue (inability of fibers to contract) as a byproduct
- why does this process exist? we need to exercise and some of the muscle fibers (not all) will inevitably run out of oxygen
- lucky for us the liver has a built in mechanism to rid the body of lactic acid though it is not as fast as we like