Ch 2&3: the cell and its Fxn Flashcards
up to slide 28
____ is an amphipathic bilayer made mostly of phospholipids
Plasma membrane
_____ separates the intercellular (protoplasm) from the extracellular enviro
Plasma membrane
_____: the membrane bound organelle that contains genetic material
nucleus
_____: jelly like substance that contains the organelles
cytoplasm
_____ makes up most of the cell in the protoplasm
water
_____ makes up part of the cytoplasm
protein
____ & ___ have a protein structure and make up the cytoskeleton
microtubules & microfilaments
Phospholipids dont like ___
water
___ creates kinks in the cell membrane and help to make the membrane more fluid
cholesterol
___ (neuro) cells are rich in cholesterol
schwann cells
What is the difference between protoplasm and cytoplasm
Protoplasm is the whole content of a cell enclosed within the cell membrane, including both the cytoplasm and nucleus.
Cytoplasm is the content of the cell except the nucleus.
_____ allows selective communication btw intracellular and extracellular compartments of the cell
plasma membrane
name 3 functions of the plasma membrane
- allows selective communication btw intracellular and extracellular compartments
- aids cellular movement
- Gives cells its form
Another name for hydrophobic
nonpolar
a non polar bear
are Fatty acids chains polar or nonpolar?
nonpolar (hydrophobic)
_____: is a sphere of phospholipids where the heads come together and the tails touch
micelle
________: is when the micelle becomes to large. Fatty acids spread out
bilayer sheet
what cell membranes are
______: are created by drug companies. They hold drugs in the center to look like a micelle. This enables the drug to move through nonpolar environments
liposome
_____ membrane proteins are intercellular and extracellular
integral
______ membrane proteins protrude bilayers
integral
____membrane proteins provide channels/pores
integral membrane proteins
____ membrane proteins act as carrier proteins in active transport
integral membrane protein
_____ membrane proteins act as receptors
integral
5 properties of integral membrane proteins
- protrde bilayer
- provide channels/ pores
- carrier protein in active transport
- enzymes
- receptors
_____ membrane proteins only attach to one layer of the cell
peripheral
____ membrane proteins can attach to integral proteins
peripheral
membrane carbs join with _____ or ____
proteins or lipids
the _____ portion of glycoproteins and glycolipids protrudes above the outer layer of the membrane
glyco
___ : refers to the loose CHO coating on the outer surface of the cell membrane
glycocalyx
4 fxn of glycocalyx’
- the glycocalyx of one cell can attach to the glycocalyx to bind the cells together
- the CHOs act as receptors substances for binding hormones
- gives the surface a negative charge –> repeling neg. molecules
- assist in immune rxn
Neatly all membrane proteins are ___
glycocalyx
glycocalyx gives the membrane a _____ charge
negative
cholesterol dissolves in hydro__ region
hydrophobic tail region
____ provide membrane fluidity
cholesterol
cholesteral can be found in ____ cells in the peripheral NS
schwann cells
the fluid mosaic model of the cell membrane illistrates that the cell membrane is:
a)
b)
a) components of the bilayer arent stuck
b) membrane make of diverse molecular components
_____: is the messaging from cell membrane to the nucleus
intracellular signalling
Long-term cellular changes require expression of ______
new genes in the nucleus
name the 2 ways to alter gene expression :
- genetic
2. epigenetic
_____: genetically altering gene expression directly on the DNA
transcription
_____: changes not on the DNA directly, but changes to gene expression
Epigenetic
_______: process by which one of the two copies of the X chromosome present in female mammals is inactivated.
x- chromosome inactivation
epigenetic change
Give two examples of epigenetic changes
x chromosome inactivation
histone acetylation/ deacetylation
DNA is wrapped around a ____protein
histone
_______ prevents DNA from being exposed and transcribed
positive charge on a histone protein
the addition of _______ groups unwraps and exposes DNA
acetyl groups
–> allows for transcription / expression
__: DNA that is wrapped around histones
chromatin
chromosomes are just bigger that we can see
_____: is a loose chromatin that is not tightly bounded and can be transcribed
euchromatin
________ : is a chromatin that is tightly bound and cant be transcribed
heterochomatin
______: helps to maintain the cell’s structure and shape
cytoskeleton
What are the three main networks of primary PROTEIN filaments
- actin filament
- intermediate filament
- microtubles
organelles can travel across ____ to get to other areas of the cell
microtubles
Microtubules are composed of polymerized ______
tubulin (a protein)
\_\_\_\_\_\_: participate in cell mobility cell division cytokinesis vesicle organelle movement cell shape
microfilaments
_____ filaments are in cells that withstand mechanical stress
intermediate filaments
_____ are known as prtein making factories
ribosomes
After DNA is _______ to mRNA , ribosomes ____ mRNA to protein
transcribed
Tranlate
Ribosomes are located in the ______ and in the ____
cytoplasm & Endoplasmic reticulum
___: is a network of tubules and flat vescicles interconnected with one another
endoplasmic reticulum
The walls of the ER are made up of ?
lipid bilayers (that contain protein)
Smooth ER fxn for the synthesis of _____
lipid substances
Rough ER are ribosomes that are a combo of RNA and proteins. They FXN to synthesis ______
glycosylation new proteins
addng CHO groups to proteins is called ______
glycosylation
What are the two sites of glycosylation in the ER?
1st in the ER
2nd in the golgi apparatus –> makes the instructions more complex
Glycosylation is the addition of a CHO to a ____
protein
Without proper glycosylation, the cell doesn’t know what to do with______
newly synthesized protein
______: are slacked layers of thin vesicles in the golgi apparatus
cisternae
_____ is known as the export system of the cell
golgi
Vesicles that pinch off from the golgi apparatus form (3) :
1.
2.
3.
- lysosomes
- secretory vesicles
- cytoplasmic components
_______ take the pritein and enzymes to the outer cell membrane to be released
secretory vesicles
made from vesiscles being pinched off from the golgi apparatus
_________: occurs whenvesiscles go to the cell membrane & through exocitosis they release what was in it
cell communication
____: is the process of cellular INGESTION by which the plasma membrane folds inward to bring sub. into the cell
endocytosis
Name three types of endocytosis
- pinocytosis
- receptor-mediated endocytosis
- phagocytosis
____: is a form of endocytosis that brings a particle into the cell by invaginating it & then suspending it within a vesicle to be fused with a lysosome
pinocytosis
________ endocytosis is when a molecule binds to specialized protein receptors on the plasma membrane
receptor-mediated endocytosis
receptors are located on small pts called ______ on the surface of cells
coated pits
The inside of the membrane of the coated pits are lined with a fibrillary protein called _____
clathrin
_______ endocytosis is when the receptors in the coated pit are full, the entire pit invaginates and forms a cated vesicle inside the cytoplasm
receptor mediated endocytosis