CH 18:Cancer Flashcards

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1
Q
A
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2
Q

Two types of tumors

A

Benign:
-Non-cancerous
-remain in one place
-surgically removed

Malignant:
-Invades/compromises normal organ/tissue function
-Increase in nucleus

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3
Q

3 groups of genes MOST likely to cause cancer

A

Proto-oncogenes
Tumor suppressor genes
Mutator genes

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4
Q

Common types of cancer

A

-Carcinomas(Occurs in epithelial tissues)
-Sarcomas(occurs in connective or muscle tissues)
-Gliomas(occurs in nervous tissues)
-Leukemias(Occurs in white blood cells)

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5
Q

Factors that lead to cancer

A

-Age
-Inherited genes
-Carcinogens
-chemicals
-radiation
-Infectious agents( hepatitis b or c)
-Diet
-Type 2 diabetics

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6
Q

Cells in the immune system do what?

A

Identify proteins

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7
Q

Immune system does what

A

defends the body against cancer

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8
Q

2 groups of chemotherapy drugs

A

Cell cycle specific(CCS)
-Kill cancer and normal cells at specific points

Cell cycle nonspecific(CCNS)
-Kill at any point in cell cycle by adding small molecules at bases of dna

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9
Q

Phases of Cell cycle specific

A

G1: death of cells
S: disrupts DNA replication
G2: interfere with DNA/ RNA synthesis
Mitosis: prevents chromosomes from separating by poisoning the mitotic spindle

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10
Q

Different chemotherapy options

A

Adjuvant - chemicals given after surgery or radiation

Neo-adjuvant – chemicals given to shrink a tumor before surgery or radiation

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11
Q

Chemotherapy( kill log) first approach

A

Late diagnosis

Treatment begins late

Prolongs survivals, but does not prevent death

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12
Q

Chemotherapy( kill log) second approach

A

Uses combination drug therapy

Begun earlier then 1st approach

Treatments are more frequent

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13
Q

Chemotherapy (kill log) 3rd approach

A

Early surgery removes primary tumor

Intense chemotherapy for several months

Reduces tumor cells to low number

Can be cured with immune system aid

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