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FCPath(SA)Haem - HaemOnc > CH > Flashcards

CH Flashcards

CH, ARCH, CHIP, ICUS, CCUS

1
Q

Definition of CH

A

Clonal Haematopoiesis
* Clonal proliferation of HSC & progenitors
* Any cause

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2
Q

Definition of ARCH

A

Age-related CH
* Aging and CH
* No cytopenias/haem malignancy

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3
Q

Definition of CHIP

A

Clonal hematopoiesis of indeterminate potential
* CH and somatic mut (VAF>2%)
* No cytopenias/haem malignancy

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4
Q

Definition of CCUS

A

Clonal cytopenia of undetermined significance
* CH and somatic mut (VAF>2%)
* Cytopenia (persistent and unexplained)
* No haem malignancy

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5
Q

Definition of ICUS

A

Idiopathic cytopenias of undetermined significance
* Cytopenia (persistent and unexplained)
* No mutation/haem malignancy

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FCPath(SA)Haem - HaemOnc (20 decks)

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