Ch. 16 - Emotional, Mood, and Behavioral Disorders Flashcards

1
Q

To be diagnosed with bipolar disorder, what must happen?

A

Manic symptoms must persist for at least 1 week

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1
Q

A depressed affect that lasts for a minimum of two weeks and is present for most of the day, every day, or almost everyday in addition to 5 other symptoms

A

Major depressive disorder

Difficulty sleeping or sleeping too much
Extremely tired; without energy
Abnormal eating patterns
Vague physical symptoms
Obsession with death
Avoidance of psychosocial and interpersonal interactions
Lack of interest in personal appearance or sex
Delusions or hallucinations
Inability to concentrate or make decisions
Feelings of despair, guilt, misery; lack of self-worth

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2
Q

Intense mood changes associated with hormonal changes after giving birth

A

Postpartum depression

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2
Q
A
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3
Q

Enhanced release of melatonin due to lower natural light levels

A

Seasonal Affective Disorder (SAD)

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4
Q

Intense mood shifts; unusual behaviors

A

Psychotic depression

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5
Q

Severe depressive illness generally requires what?

A

Interpersonal and cognitive-behavioral
Psychodynamic therapies

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6
Q

Focus on the patient’s disturbed personal relationships that both cause and exacerbate the depression

A

Interpersonal therapies

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7
Q

Helps patients change the negative styles of thought and behavior often associated with their depression

A

Cognitive behavioral therapy

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8
Q

Focus on resolving the patient’s internal conflicts

A

Psychodynamic therapies

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9
Q

For patients with serious and life-threatening mood disorders who are unresponsive to pharmacotherapy and psychotherapy

A

Electroconvulsive therapy (ECT)

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10
Q

Inhibit the reuptake of neurotransmitters (norepinephrine and serotonin) into the presynaptic nerve terminals

A

TCAs & SNRIs

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11
Q

Inhibit MAO enzyme activity inside the presynaptic nerve terminals

A

MAOIs

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12
Q

Have an effect of enhanced catecholamine release

A

MAOIs

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13
Q

Block the reuptake of serotonin into presynaptic nerve terminals

A

SSRIs

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14
Q

Enzymes that terminate the action of norepinephrine

A

MAO & COMT

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15
Q

Classes of Antidepressant Drugs

A

SSRIs
SNRIs and other atypical antidepressants
TCAs
MAOIs

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16
Q

Ex. citalopram (Celexa)
fluoxetine (Prozac)
paroxitine (Paxil)

A

Selective Serotonin Reuptake Inhibitors (SSRI)

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17
Q

Ex. Bupropion (Wellbutrin)
duloxetine (Cymbalta)
venlafaxine (Effexor)

A

Atypical antidepressants, including serotonin-norepinephrine reuptake inhibitors (SNRI)

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18
Q

Ex. amitriptyline (Elavil)
imipramine (Tofranil)

A

Tricyclic antidepressants (TCA)

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19
Q

Ex. phenelzine (Nardil)

A

Monoamine Oxidase Inhibitors (MAOI)

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20
Q

Characterized by episodes of depression alternating with episodes of mania

A

Bipolar disorder (manic-depression)

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21
Q

Lack of energy
sleep disturbances
abnormal eating patterns
Feelings of despair
guilt
hopelessness

A

Depressive symptoms

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22
Q

Inflated self-esteem or grandiosity
Decreased need for sleep
Increased talkativeness
Flight of ideas; subjective feeling that thoughts are racing
Distractibility
Increased goal-directed activity
Excessive involvement in pleasurable activities that have high potential for painful consequences

A

manic symptoms

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23
Work by moderating extreme shifts in emotions between mania and depression.
mood stabilizers
24
Why should Bipolar disorder never be treated with antidepressants alone?
it will cause the patient to have manic cycles
25
Mood Stabilizer main drug
lithium (Eskalith)
26
lithium (Eskalith) MOA
affects sodium transport across cell membranes
27
Acts like sodium in the body: so adverse effects are similar to those of hyponatremia
lithium (Eskalith)
28
Why does lithium (Eskalith) require frequent blood draws
To check serum levels b/c lithium (Eskalith) has a narrow therapeutic range
29
How often do you check serum levels for the patient taking lithium (Eskalith)?
Every 4-5 days, after any change of dose, or initiation of therapy
30
Therapeutic concentrations of lithium (Eskalith)
range from 0.6 to 1.5 mEq/L
31
Persistent GI upset (nausea, vomiting, abdominal pain), increased urination, and confusion
Early signs of lithium toxicity
32
Nystagmus, convulsions, ataxia, coma
Late signs of lithium toxicity
33
Drugs for the treatment of bipolar disorder
antiseizure drugs: atypical antipsychotic drugs
34
Valproic acid (Depakene, Depakote) cabamazapine (Tegretol) lamotrigine (Lamictal)
antiseizure drugs used for treatment of bipolar disorder
35
heart block aplastic anemia respiratory depression SJS toxic epidermal necrolysis coma death (overdose) liver failure pancreatitis exfoliative dermatitis
serious adverse effects of antiseizure drugs
36
Dizziness ataxia somnolence headache nausea diplopia blurred vision sedation drowsiness nausea vomiting prolonged bleeding time
side effects of antiseizure drugs
37
Risperidone (Risperdal) aripiprazole (Abilify) Seroquel Zyprexa
Atypical antipsychotics used for bipolar disorder
38
tachycardia parkinsonism transient fever akathisia insomnia sedation dizziness nausea vomiting constipation
Side effects of atypical antipsychotics used for treatment of bipolar disorder
39
agranulocytosis increased risk of death in older adults with demential-related psychosis neuroleptic malignant syndrome (rare)
Serious adverse effects of atypical antipsychotics used for the treatment of bipolar disorder
40
Neurodevelopmental/Behavioral disorder
ADHD
41
Easy distractibility Failure to receive or follow instructions Inability to focus on one task at a time Difficulty remembering Frequent loss or misplacement of personal items Excessive talking; interrupting Inability to sit still Impulsiveness Sleep disturbance
Symptoms of ADHD/Developmentally inappropriate behaviors
42
Methylphenidate (Ritalin, Concerta, Daytrana, Metadate, Methylin) Adderall Vyvanse
CNS Stimulants
43
CNS stimulants MOA
heightens awareness, increases focus
44
insomnia nervousness anorexia weight loss irritability palpitations
Side effects of CNS stimulants
45
Psychological dependence circulatory collapse sudden death (reported in children with structural cardiac abnormalities)
Serious adverse effects of CNS stimulants
46
To reduce the risk of dependence and evaluate need, the nurse should educate their patient to do what when taking CNS stimulants.
take drug-free "holidays"
47
Similar efficacy to stimulants with reduced risk of dependence.
Non-stimulants for ADHD treatment
48
Can be used as monotherapy or adjuvant
Non-stimulants for ADHD treatment
49
atomoxetine (Strattera) clonidine guanfacine (Intuniv)
Non-stimulants for ADHD treatment
50
headache insomnia decreased appetite dry mouth vomiting upper abdominal pain severe liver injury
Adverse effects of Nonstimulants for the treatment of ADHD
51
Black Box Warning for atomoxetine (Strattera)
suicidal ideation
52
Nervousness Anxiety GI Upset Fatigue
side effects for only SSRIs
53
Increased BP & HR Sweating Agitation Tremor Vomiting Increased Appetite
side effects for only SNRIs
54
Sedation Mydriasis - dilation of the eye
Side effects for only TCAs
55
Dry mouth Sexual Dysfunction
Side effects for: SSRIs SNRIs TCAs MAOIs
56
Headache Somnolence
Side effects for: SSRIs SNRIs
57
Urinary retention
Side effects for: TCAs MAOIs
58
Nausea Insomnia
Side effects for: SSRIs SNRIs MAOIs
59
Dizziness
Side effects for: SSRIs SNRIs TCAs
60
Constipation Blurred Vision Drowsiness Orthostatic hypotension
Side effects for: SNRIs TCAs MAOIs