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Pharmacology - Spring 2024 > Ch. 14 Drug Cards - Anxiety & Insomnia > Flashcards

Ch. 14 Drug Cards - Anxiety & Insomnia Flashcards

1
Q

lorazepam (Ativan) therapeutic class

A

Sedative-hypnotic; anxiolytic; anesthetic adjunct

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2
Q

lorazepam (Ativan) pharmacologic class

A

Benzodiazepine; GABA a-receptor agonist

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3
Q

lorazepam (Ativan) action

A

Potentiates the effects of GABA

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4
Q

One of the most potent benzodiazepines

A

lorazepam (Ativan)

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5
Q

lorazepam (Ativan) contraindications

A

Acute narrow-angle glaucoma
Close-angle glaucoma
Misuse or excessive use of drugs
Liver disease
Impaired brain function
Thoughts of suicide

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6
Q

lorazepam (Ativan) drug interaction

A

Interacts with multiple drugs

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7
Q

escitalopram (Lexapro) Therapeutic Class

A

Antidepressant; anxiolytic

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8
Q

escitalopram (Lexapro) Pharmacologic Class

A

SSRI

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9
Q

escitalopram (Lexapro) indications

A

General Anxiety Disorder (GAD) & major depression

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10
Q

escitalopram (Lexapro) increases the availability of what?

A

serotonin

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11
Q

Selective inhibition of serotonin reuptake results in antidepressant activity without production of symptoms of sympathomimetic or anticholinergic activity

A

escitalopram (Lexapro) MOA

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12
Q

escitalopram (Lexapro) contraindications

A

Breastfeeding and within 14 days of MAOI therapy

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13
Q

escitalopram (Lexapro) interactions

A

Avoid MAOIs - can cause serotonin syndrome

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14
Q

Autonomic hyperactivity, hyperthermia, rigidity, diaphoresis, and NMS

A

Markers of Serotonin syndrome

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15
Q

zolpidem (Ambien, Edluar, Intermezzo) Therapeutic Class

A

Sedative-hypnotic

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16
Q

zolpidem (Ambien, Edluar, Intermezzo) Pharmacologic Class

A

Nonbenxodiazepine GABAa receptor agonist; nonbenzodiazepine, nonbarbiturate CNS depressant

17
Q

zolpidem (Ambien, Edluar, Intermezzo) indication

A

ONLY this: Short-term insomnia management (7-10 days)

18
Q

zolpidem (Ambien, Edluar, Intermezzo) patient education

A

take immediately before bedtime - rapid onset of 7-27 minutes

19
Q

Daytime sedation
Confusion
Amnesia
Dizziness
Depression with suicidal thoughts
Nausea
Vomiting

A

zolpidem (Ambien, Edluar, Intermezzo) Adverse Effects

20
Q

Hallucination
Sensory distortion
Sleepwalking
Nocturnal eating

A

zolpidem (Ambien, Edluar, Intermezzo) adverse neuropsychiatric reactions

21
Q

True or False: Women have a significantly higher serum zolpidem concentration than men

22
Q

zolpidem (Ambien, Edluar, Intermezzo) drug interactions

A

Increase sedation when used concurrently with other CNS depressants

Pharmacology - Spring 2024 (8 decks)

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