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Pharmacology - Spring 2024 > Ch. 16 Drug Cards - Emotional, Mood, and Behavioral Disorders > Flashcards

Ch. 16 Drug Cards - Emotional, Mood, and Behavioral Disorders Flashcards

1
Q

sertraline (Zoloft) Therapeutic Class:

A

Antidepressant

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2
Q

sertraline (Zoloft) Pharmacologic Class

A

Selective serotonin reuptake inhibitor (SSRI)

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3
Q

sertraline (Zoloft) is used for what?

A

treatment of depression, anxiety, obsessive-compulsive disorder, and panic.

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4
Q

sertraline (Zoloft) MOA

A

inhibit the reuptake of serotonin in the brain.

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5
Q

How would you administer sertraline as an oral liquid?

A

mix with water, ginger ale, lemon/lime soda, lemonade, or orange juice.

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6
Q

When administering sertraline (Zoloft), when should the nurse take extreme precautions?

A

in patients with:
cardiac disease
hepatic impairment
seizure disorders
suicidal ideation
mania
hypomania.

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7
Q

sertraline (Zoloft) interactions with MAOIs

A

may cause neuroleptic malignant syndrome, extreme hypertension, and serotonin syndrome

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8
Q

confusion, anxiety, restlessness, hypertension, tremors, sweating, hyperpyrexia, or ataxia.

A

S&S of serotonin syndrome

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9
Q

Patient education for sertraline (Zoloft) & MAOIs

A

Do not take concurrently w/ a MAOI or within 5 weeks of discontinuing MAOI meds

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10
Q

imipramine (Tofranil) Therapeutic Class:

A

Antidepressant; treatment of nocturnal enuresis in children

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11
Q

imipramine (Tofranil) Pharmacologic class

A

Tricyclic Antidepressant (TCA)

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12
Q

Side effect of TCAs

A

paradoxical diaphoresis

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13
Q

When a patient is prescribed imipramine (Tofranil), diaphoresis may not be a reliable indicator of what?

A

other disease states such as hypoglycemia.

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14
Q

imipramine (Tofranil) causes what?

A

anticholinergic effects

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15
Q

imipramine (Tofranil) MOA

A

blocks the reuptake of serotonin and norepinephrine

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16
Q

Unlabeled uses of imipramine (Tofranil)

A

intractable pain
anxiety disorders
withdrawal syndromes from alcohol and cocaine

17
Q

Patient education for imipramine (Tofranil)

A

Therapeutic effectiveness may not occur for 2 or more weeks.

18
Q

Photosensitivity

A

Side effect of imipramine (Tofranil)

19
Q

imipramine (Tofranil) contraindications

A

Should not be used in cases of:
acute recovery after MI
defects in bundle-branch conduction
narrow-angle glaucoma
severe renal or hepatic impairment.

Patients should not use this drug within 14 days of discontinuing MAOIs.

20
Q

imipramine (Tofranil) drug interactions

A

many
CNS depressants - sedation
cimetidine (Tagamet) - increased serum levels and possible toxicity
clonidine - reverse antihypertensive effects and potentiate CNS depression
Oral contraceptives - increase or decrease imipramine levels
Disulfiram - delirium and tachycardia

21
Q

altered blood glucose tests.
Elevation of serum bilirubin and alkaline phosphatase is likely.

A

imipramine (Tofranil) lab tests

22
Q

phenelzine (Nardil) Therapeutic classification

A

antidepressants

23
Q

phenelzine (Nardil) Pharmacologic classification

A

MAOI

24
Q

Washout periods of 2 to 3 weeks are required before introducing other drugs.

A

phenelzine (Nardil) Administration alerts

25
Q

Abrupt discontinuation of phenelzine (Nardil) may cause what?

A

rebound hypertension.

26
Q

Patient education for the patient taking phenelzine (Nardil)

A

Drug effects may persist for 2 to 3 weeks after therapy is discontinued.

27
Q

Severe hypertension may occur when ingesting foods containing tyramine.

A

phenelzine (Nardil) adverse effects

28
Q

phenelzine (Nardil) contraindications

A

Patients with:
cardiovascular or cerebrovascular disease
hepatic or renal impairment

29
Q

phenelzine (Nardil) drug interactions

A

interacts with MANY drugs

30
Q

methylphenidate (Ritalin, Concerta) Therapeutic Classification:

A

Attention deficit–hyperactivity disorder (ADHD) drug

31
Q

methylphenidate (Ritalin, Concerta) Pharmacologic Classification

A

CNS stimulant

32
Q

methylphenidate (Ritalin, Concerta) Controlled Substance Schedule

A

Schedule II drug

33
Q

methylphenidate (Ritalin, Concerta) actions

A

heightened alertness with focus and attention

34
Q

Activation is partially achieved by the release of neurotransmitters such as norepinephrine and dopamine. Impulsiveness, hyperactivity, and disruptive behavior are usually reduced within a few weeks.

A

methylphenidate (Ritalin, Concerta) MOA

35
Q

methylphenidate (Ritalin, Concerta) adverse effects in a non-ADHD patient

A

nervousness and insomnia

36
Q

methylphenidate (Ritalin, Concerta) Black Box Warning

A

Scheule II drug with high abuse potential

37
Q

methylphenidate (Ritalin, Concerta) drug interactions

A

Interacts with many drugs

Pharmacology - Spring 2024 (8 decks)

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