Ch 15: Circulatory System Flashcards
It has three general functions:
- transports and delivers nutrients and waste around the body
- regulation of fluid, electrolyte balance and body temperature
- protection from infection and excessive clotting
It has several characteristics:
- color varies from bright red to blue red depending on oxygen levels
- amount varies based on size, gender and age, averaging 4 to6 L
- pH between 7.35-7.45
- three times more viscous than water
It contains two parts:
- liquid plasma
- Formed elements or cells
Blood
It is a pale yellow fluid mostly water, also includes proteins, ions, nutrients, gases and wastes. These proteins regulate fluid volume and protect the body from pathogens and prevents excessive blood loss
Serum is this minus the clotting proteins
Plasma
Is made up of:
- RBC’s
- WBC’s
- platelets\thrombocytes
Blood cells
formed elements
This is the percentage of RBC in a sample of blood, usually 45%, plasma will be on top, WBC and platelets in the middle Buffy coat with RBC at the bottom
hematocrit
Blood cell formation
Two examples:
- red bone marrow found in flat bones and ends of long bones
- lymphatic tissue such as the spleen, lymph nodes, and thymus
Hematopoiesis
These can differentiate into either of RBC, WBC or a platelet
Blood stem cells
Occurs with certain procedures or drugs
example: chemotherapy
Myelosuppression
This causes excess RBC’s and thickened blood
Bone marrow overactivity
This type of blood cell is the most numerous in the body and transports oxygen.
Shape: large disc shaped, flexible and allowing cells to squeeze through tiny blood vessel’s supplying oxygen to all tissue cells
Red blood cells
RBC’s
A type of red blood cells that Attaches to oxygen
When the blood is well oxygenated blood is bright red
When the blood is poorly oxygenated blood is blue read; cyanosis
Substances essential for production:
- iron; iron deficiency anemia
- vitamin B 12; lack of intrinsic factor causes pernicious anemia
- folic acid; Folic acid anemia
Regulation of production is controlled by hormone erythropoietin
Lifespan is 120 days
No nucleus therefore they cannot reproduce
The spleen destroys old worn out cells.
Hemoglobin
A type of blood cell that are large round cells that contain nuclei, but lack hemoglobin
Several functions:
- phagocytosis; removes dead tissue and debris
- leukocytosis; an increase in the number of WBC
- diapedesis; allows WBC’s to Leave the blood vessels and move toward site of infection
White blood cells
A function of WBCs
removes dead tissue and debris
leaves behind a collection of dead neutrophils and pathogen‘s, Parts of cells and fluid-pus
phagocytosis
A function of WBCs
an increase in the number of WBC
leukocytosis
A function of WBC
allows WBC’s to Leave the blood vessels and move toward site of infection
diapedesis
A type of WBC; granulocytes
They make up 55% to 70% of total wbc
Functions;
- phagocytosis; leaves behind a collection of dead neutrophils and pathogen‘s, Parts of cells and fluid-pus
- An increase in the number of immature this indicates an infection
Neutrophils
A type of WBC; granulocytes and They make up less than 1% of blood cells
Releases histamine and heparin
basophils
A type of W BC; granulocytes which make up between 1% and 3% of blood cells
Inflammatory response, elevated in persons with allergies
Eosinophils
Laboratory test that provide information about blood
It gives a normal range of numbers for RBC’s, WBC’s and platelets, hemoglobin, hematocrit, percentage of reticulate and WBC’s differential
Complete blood count
CBC
Slows or stops the flow of blood
Blood vessel spasm
Caused by platelets sticking together
Aspirin has an antiplatelet effect
Formation of a platelet plug
This is performed by a series of chemical reactions forming a fibrous net to stop the bleeding
Functions include:
-thrombus; blood clot
-embolus;A traveling clot
-anticoagulants; prevents excessive clot formation
Example: heparin, aspirin Coumadin
once clots have formed, clot busting drugs called TPA‘s Are given to prevent heart attacks and strokes
Blood clotting
These are located on the RBC membrane
ABO grouping gives four blood types: A, B, AB and O
Antigens and the blood types
Occurs when Blood types are missed matched
Agglutination
Burstein or dissolving of RBC’s
Hemolysis
This blood type is called the universal donor and is the most common blood type
Blood type O
This blood type is called the universal recipient and is the least most common blood type
Blood type AB
This problem occurs when a pregnant mother is Rh(+) and her second baby is Rh( - ) because blood will develop and try to destroy the blood next time around
The pregnant mother is given RhoGAM during pregnancy to prevent antibody formation which causes jaundice and hemolysis of the babies RBC’s
Hemolytic disease of the newborn
HDN
Located on the RBC membrane
There r 4 types: A, B, AB, O
Each type has antibodies for incompatible types
Blood types
Occurs when blood types are mismatched and different antibodies are mixed 2gether
Agglutination
Bursting or dissolving of RBC’s
Hemolysis
In order to avoid agglutination of blood, blood type must be known b4 transfusions
Blood types O is called the “universal donor” & most common blood type
Blood type AB is called the ”universal recipient” and least common blood type
Compatibility and incompatibility of blood types
Not normally a problem unless a Rh(-) person is exposed to Rh(+) blood
Antibodies to Rh(+) blood will develop and try to destroy the blood next time around
In a Rh(-) pregnant mother, this could b disastrous for the 2nd baby that is Rh(+)
RH classification system
Hollow, muscular organ, approximately the size of a persons fist fist, weighs less than 1 pound
Average rate of 72 BPM, will be over 3 million times if you live to 75 years of age
Sits within the chest between the lungs in a space called the mediastinum
Base-upper flat portion located at the level of the second rib
Apex-lower pointed end located at the fifth intercostal space
Important to know precise location for performing EKG and CPR
Made up of 3 layers:
- endocardium
- myocardium
- epicardium
Function, location and size of the heart
Lining of the heart chambers consists of lining that is continuous with the blood vessels
Endocardium
Thickest layer composed of cardiac muscle that actually contracts and pumps blood through the blood vessels
Myocardium
Sling like structure; double stack of serous membrane
Epicardium
Visceral pericardium
Is located between the layers of the heart, it allows the heart to beat in its sack without friction
Serous fluid
Inability of the heart to pump a sufficient amount of blood to the body, must insert a needle into the pericardial space and aspirate the excess fluid
Cardiac tamponade
One part of the heart and Part of pulmonary circulation
Receives oxygen poor blood from the venae cavae and sends it to the lungs to exchange O2with CO2, then back to that side of the heart
Right side of the heart
One part of the heart and Part of systemic circulation
Supplies oxygen rich blood to all body tissues and organs, then back to that side of the heart
Left side of the heart
an upper chamber of the heart that receives blood into the heart
Upper chambers that receive blood into the heart. It receives oxygen poor blood from the superior and inferior venae cavae and sends it through the tricuspid valve into the right ventricle
Right atrium
Receives blood from the head and upper body region
Superior vena cava