Ch. 13: Integumentary Function Flashcards
what are the structures of the integumentary system?
skin, hair, nails, mucous membranes, and glands
what are the disorders that can occur with the integumentary system?
congenital defects, advancing age, inflammation, infections, and cancers
what is the hypodermis made of?
soft fatty tissue as well as blood vessels, nerves, and immune cells
what is the dermis made of?
dense irregular connective tissue and very little fat tissue. contains nerves, hair follicles, smooth muscle, glands, blood vessels, and lymphatic vessels
secrete sweat through skin pores in response to the sympathetic nervous system
eccrine glands or merocrine glands
sweat glands that open into hair follicles in the axillae, scalp, face, and external genitalia
apocrine glands
skin anomalies that are present at birth or shortly after. most are harmless and may even shrink or disappear with age
birth marks
what are the ways in which birthmarks may appear?
may be flat or raised, have regular or irregular borders, and have different shades of coloring including black, tan, brown, pale blue, pink, red, or purple
birthmarks that arise from blood vessels that have not formed correctly. what color are these most likely to be?
vascular birthmarks are usually red
what are the different types of vascular birthmarks?
macular stains, port-wine stains, hemangiomas
most common type of vascular birthmark. faint red marks that usually occur on forehead, eyelids, posterior neck, nose, upper lip, or posterior head
macular stains
when may macular stains be more noticeable?
when the child is crying
by what age are most macular stains gone?
most often fade on their own by 2 years of age, but they may last into adulthood
what are macular stains also known as?
salmon patches, angel kisses, and stork bites
birthmarks that appear as a bright red patch or a nodule of extra blood vessels in the skin
hemangioma or strawberry
what color with deep hemangiomas be? why?
bluish because they involve deeper blood vessels
when do hemangiomas grow?
grow during the first year of life and then usually recede over time
where are many hemangiomas found?
on the head and neck, but they can be anywhere
when will hemangiomas cause complications?
when their location interferes with sight, feeding, breathing, or other bodily functions
discolorations that look like wine was spilled on an area of the body
port-wine stains
where do port-wine stains most often occur?
face, neck, arms, and legs
how do port-wine stains change over time?
can be any size, but only grow as the child grows. tend to darken over time and can thicken and have a cobblestone texture in mid adulthood unless treated
will port-wine stains resolve on their own? when should they be assessed for complications?
no, they will not resolve spontaneously. those occuring near the eye should be assessed for possible complications
birthmarks made of clusters of pigmented cells, which cause color in skin
pigmented birthmarks
what colors are pigmented birthmarks?
can be many different colors from tan to brown, gray to black, or even blue
what are the most common pigmented birthmarks?
cafe au lai spots, mongolian spots, and moles
very common birthmarks that are the color of coffee
cafe au lait spots
when should a child with cafe au lait spots be evaluated?
if he or she has several spots larger than a quarter - this can be a sign of neurofibromatosis
flat, bluish-gray patches often found on the lower back or buttocks and are more common in individuals with darker complexions
mongolian spots
do mongolian spots usually fade?
yes, they usually fade often without treatment by school age
general term for brown nevi
mole
when present at birth, what is a mole called
a congenital nevus and will last a life time
how may a mole appear?
may be tan brown, or black; can be flat or raised; may have hair growth
what can disorders involving melanin result in?
alterations in skin coloring. can leave skin vulnerable to the harmful effects of UV light.
what the disorders involving melanin?
albinism and vitiligo
recessive condition that results in little or no melanin production
albinism
why do all forms of albinism cause problems with eye development and function?
melanin plays a role in the development of certain optical nerves
what are the two major types of albinism and how are they different?
type I - caused by defects that affect melanin production
type II - caused by a defect in the P gene; have slight coloring at birth
what is the most severe form of albinism? what do people with this condition look like?
oculocutaneous albinism. have white or pink hair, skin, and iris color and vision problems
type of albinism that affects only the eyes. the affected person’s skin and eye colors are usually normal but there is no coloring of the retina
ocular albinism type I
type of albinism caused by a single gene; it can occur with a bleeding disorder as well as with lung and bowel diseases
Hermansky-Pudlak syndrome
type of albinism that causes a lack of coloring all over the skin, but not complete
Chediak-Higashi syndrome
type of localized albinism that causes small areas without skin coloring
Tuberous sclerosist
type of localized albinism where often a lock of hair that grows on the forehead is affected, or no coloring is present in one or both irises
Waardenburg’s syndrome
what are the clinical manifestations of albinism?
skin changes - many result in milky white skin, but skin pigmentation can range from white to nearly the same as relatives without albinism.
hair changes - hair can range from very white to brown. may also have hair that is reddish, yellow, or brown
eye changes - eye color ranges from very light blue to brown and may change with age. somewhat translucent. can appear to be red because of red reflex.
vision changes - nystagmus, strabismus, extreme nearsightedness or farsightedness, photobia, astigmatism, functional blindness
will a person’s skin always stay the same color with they have albinism?
no, melanin production may begin or increase during childhood and adolescence, resulting in slight increases in pigmentation; hair color may also change by early adulthood
does albinism impair intellectual development?
no, but people with albinism often experience feelings of social isolation and may experience descrimination. visual issues may become an educational challenge
rare condition characterized by small patchy areas of hypopigmentation
vitiligo
when does vitiligo occur?
when the cells that produce melanin die or no longer form melanin, causing slowly enlarging white patches of irregular shapes on the skin
what races does vitiligo affect?
affects all races, but is more easily seen in people with darker pigmented skin
what are potential causes of vitiligo?
autoimmune conditions, genetic influences, sunburn, and emotional stress. has also been associated with perinicious anemia, hypothyroidism, and Addison’s disease
where does depigmentation of vitiligo usually develop first?
on sun exposed areas
when does vitiligo usually first appear?
between 10 and 30 years of age
vitiligo usually appears in one of three patterns. what are these patterns?
focal - depigmentation is limited to one or a few areas of the body
segmental - depigmentation occurs on only one side of the body
generalized - depigmentation is widely spread across many parts of the body, often symmetrically
what are the clinical manifestations of vitiligo?
patchy skin depigmentation, depigmentation of the hair, mucous membranes, and retina
what changes in sensation occur with aging?
pain, vibration, cold, heat, pressure, and touch sensations usually decrease. this may be related to decreased blood flow
what things can influence age related changes to the skin?
environmental factors, genetic makeup, and nutrition contribute to changes, but the greatest single contributing factor is sun exposure
who are more likely to show aging skin changes?
blue-eyed, fair-skinned people are more likely to show these changes than people with darker, more heavily pigmented skin
what happens to the epidermis with aging?
it thins, but the number of cell layers remain unchanged. the number of melanocytes decreases, but the remaining melanocytes increase in size
what do age related changes in the connective tissue cause?
reduced skin strength and elasticity, especially in sun exposed areas of the skin
what happens to the blood vessels in the dermis with aging?
they become fragile, which can lead to bruising, cherry angiomas, and other similar conditions
what age related changes occur in the sebaceous glands?
decreased production of sebum which can lead to difficulty maintaining skin moisture resulting in dryness and itching
what age related changes occur in the subcutaneous layer? what can these cause?
thins with age. increases risk of skin injury and reduces the ability to maintain body temperature. this layer also absorbs some medications, so loss of this layer changes the actions of these medications
what age related changes occur with sweat glands? what can this cause?
produce less sweat. causes difficulty controlling body temperature