CH 12 Antimicrobials Flashcards
Gram pos bacteria stain what color
Purple
Gram neg bacteria stains what color
Red
Aminoglycosides MOA
Bactericidal and inhibit protein synthesis
Aminoglycosides drugs include
Amikacin and gentamicin
Uses for Aminoglycosides include
Gm neg, aerobic infections
Some adverse effects of Aminoglycosides include
Otoxicity, nephrotoxicity, disruption of gut flora
Cephalosporin drugs include
Cephalexin, cefazolin (first gen)
Convenia and simplicef (third gen)
Adverse effects of cephalosporin drugs include
Allergic reaction or GI upset
1st gen cephalosporin drugs treat
Very gram + bacteria
2nd gen cephalosporin drugs treat
Broad bacteria
3rd gen cephalosporin drugs treat
Gram neg
Cefovecin=
Convenia
Cefpodoxime=
Simplicef
Macrolide drugs include
Erythromycin and tylosin
Adverse effects of macrolides
Fatal entertoxemia (hind gut fermenters)
Cephalosporin drug MOA
Bactericidal, inhibit cell wall synthesis
Mainly used for gm pos bacteria
Macrolide drugs are mainly used for
Gm pos and associated with the respiratory track
Penicillin MOA
Bactericidal, inhibits cell wall synthesis
Macrolides inhibit
Protein synthesis
Penicillin adverse side affects include
GI upset or allergic reaction
Tetracycline drugs are
Time dependent
Tetracyclines MOA
Inhibit protein synthesis and becteriostatic. Penetrate most tissues and fluids
Tetracycline drugs =
Tetracycline, doxycycline
Lincosamides MOA
Bacteriostatic at low doses and becteriocidal at high doses. Inhibit protein synthesis.
Lincosamide drug =
Clindamycin
Fluoroquinolone drugs =
Enrofloxacin and orbifloxacin
