Analgesics

Question 1

What is the pain pathway ?

Answer 1

Transduction -> transmission-> modulation-> perception

Question 2

What is the purpose of analgesics

Answer 2

Balanced anesthesia and pain management

Question 3

A drug with good affinity for the receptor and the ability to produce intrinsic effect

Answer 3

Agonist

Question 4

A drug with good affinity but little or no intrinsic effect

Answer 4

Antagonist

Question 5

This opioid is most often given in patches or CRI because it is short acting. Pure MU agonist. Last 30min-2hours.

Answer 5

Fentanyl

Question 6

Short acting mixed agonist/antagonist

Answer 6

Butorphanol

Question 7

Partial Mu agonist and kappa antagonist. Last 6-8hrs, given SQ,IM, IV, transmucosal. Not as strong.
Least likely to produce negative effects

Answer 7

Buprenorphine

Question 8

Partial agonist/antagonist strong kappa agonist. Short acting analgesic 30-60min. Mostly used for sedation. Can be given IM or IV

Answer 8

Butorphanol