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Pharmacology > Blood Modifying And Chemotherapy > Flashcards

Blood Modifying And Chemotherapy Flashcards

1
Q

Substances that tend to promote an increase in oxygen carrying capacity of blood

A

Hematinics

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2
Q

Erythropoietin does what

A

Mimic the bodies hormone that is released by the kidneys to stimulate RBC production by bone marrow

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3
Q

What mineral is necessary for the production of RBCs

A

Iron

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4
Q

What is used for piglets experiencing anemia and other mild anemias

A

Iron

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5
Q

MOA of androgens

A

Promote tissue anabolism, weight gain and RBC production

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6
Q

Androgens are used for

A

CRF (less expensive than erythropoietin, but controlled)

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7
Q

Erythropoietin is used

A

In CRF

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8
Q

CRF =

A

Chronic Renal Failure

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9
Q

Whole blood MOA

A

Transfusion to increase RBC

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10
Q

Blood substitutes MOA

A

Hemoglobin based oxygen carrier solutions (expensive but long self life and universally compatible)

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11
Q

Why does coagulation happen in the body

A

To inhibit the loss of vital blood constituents from the circulatory system

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12
Q

What is fibrinolysis

A

The body’s natural process of breaking down clots

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13
Q

List the process of coagulation

A

Mechanical stage
Chemical stage
Fibrinolysis

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14
Q

MOA of anticoagulants

A

Inhibit clot formation

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15
Q

Types of anticoagulants include

A

Green tops (heparin), purple tops(EDTA), coumarin derivatives, antiplatelets

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16
Q

Use of coumarin derivatives

A

Management of throtmbolism

17
Q

Use of Antiplatelet drugs

A

Inhibit platelet stickiness and clumping. Thromboembolism prevention

18
Q

Antiplatlet drug =

A

Aspirin CAUTION IN CATS

19
Q

Hemostatic agents MOA

A

Promote clot formation

20
Q

Topical hemostatic drugs=

A

Silver nitrate sticks, quick stop

21
Q

Parenteral hemostatic drugs use

A

Rat poisoning

22
Q

Adverse reactions for Parenteral hemostatics are

A

Anaphylactic, bleeding at inj site, hypotension, bradycardia if given too fast

23
Q

Anticoagulant antagonists =

A

Parenteral agents for heparin overdose and rat or Coumarin overdose

24
Q

Fibrinolytic MOA

A

Dissolve clots

25
Q

Fibrinolytic uses

A

Thrombosis

26
Q

Neoplasia =

A

Abnormal growth of tissue into a mass that is not responsive to normal cellular mechanisms

27
Q

Tumor is

A

Any tissue mass or swelling (very broad term)

28
Q

Benign tumor =

A

Grow locally, usually not invasive and rarely causes mortality

29
Q

Malignant =

A

Cancer

30
Q

Metastasis

A

Movement of cancer to other tissues in the body

31
Q

What part of the cell cycle is affected by alkylating agents

A

No specific phase

32
Q

What part of the cell cycle is affected by anti metabolic

A

Synthesis phase

33
Q

Which blood cells carry oxygen

A

RBC

34
Q

Which blood cells form clots

A

Platelets

35
Q

Which part of the cell cycle is affected by antitublins

A

Mitosis phase

Pharmacology (13 decks)

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