Blood Modifying And Chemotherapy Flashcards
Substances that tend to promote an increase in oxygen carrying capacity of blood
Hematinics
Erythropoietin does what
Mimic the bodies hormone that is released by the kidneys to stimulate RBC production by bone marrow
What mineral is necessary for the production of RBCs
Iron
What is used for piglets experiencing anemia and other mild anemias
Iron
MOA of androgens
Promote tissue anabolism, weight gain and RBC production
Androgens are used for
CRF (less expensive than erythropoietin, but controlled)
Erythropoietin is used
In CRF
CRF =
Chronic Renal Failure
Whole blood MOA
Transfusion to increase RBC
Blood substitutes MOA
Hemoglobin based oxygen carrier solutions (expensive but long self life and universally compatible)
Why does coagulation happen in the body
To inhibit the loss of vital blood constituents from the circulatory system
What is fibrinolysis
The body’s natural process of breaking down clots
List the process of coagulation
Mechanical stage
Chemical stage
Fibrinolysis
MOA of anticoagulants
Inhibit clot formation
Types of anticoagulants include
Green tops (heparin), purple tops(EDTA), coumarin derivatives, antiplatelets
Use of coumarin derivatives
Management of throtmbolism
Use of Antiplatelet drugs
Inhibit platelet stickiness and clumping. Thromboembolism prevention
Antiplatlet drug =
Aspirin CAUTION IN CATS
Hemostatic agents MOA
Promote clot formation
Topical hemostatic drugs=
Silver nitrate sticks, quick stop
Parenteral hemostatic drugs use
Rat poisoning
Adverse reactions for Parenteral hemostatics are
Anaphylactic, bleeding at inj site, hypotension, bradycardia if given too fast
Anticoagulant antagonists =
Parenteral agents for heparin overdose and rat or Coumarin overdose
Fibrinolytic MOA
Dissolve clots
Fibrinolytic uses
Thrombosis
Neoplasia =
Abnormal growth of tissue into a mass that is not responsive to normal cellular mechanisms
Tumor is
Any tissue mass or swelling (very broad term)
Benign tumor =
Grow locally, usually not invasive and rarely causes mortality
Malignant =
Cancer
Metastasis
Movement of cancer to other tissues in the body
What part of the cell cycle is affected by alkylating agents
No specific phase
What part of the cell cycle is affected by anti metabolic
Synthesis phase
Which blood cells carry oxygen
RBC
Which blood cells form clots
Platelets
Which part of the cell cycle is affected by antitublins
Mitosis phase
