Cerebellum Flashcards

1
Q

Which tract is the only cerebllar tract with afferent fibers into the superior peduncle

A

Anterior spinocerebellar

Origin: ascends in contralateral spinal cord (t12-L5)

Terminates: vermis and intermediate zone - ipsilateral

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2
Q

Which tract is the only cerebellar tract with affarent fibers from the middle peduncle?

A

Pontocerebellar

Origin: Pontine Nuclei

Termination: ant and post lobes - contralateral and vermis - ipsilateral

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3
Q

Major inputs to the cerebellum come in via teh _______ and _______ fibers

A

Major inputs to the cerebellum come in via the mossy and climbing fibers

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4
Q

Major output from the cerebellum are via ______ fibers to the _____ and _____.

The cerebellum ____[does/doesn’t] have direct connection to the spinal cord

A

Major output from the cerebellum are via purkinje fibers to the thalamus and red nucleus.

The cerebellum DOES NOT have direct connection to the spinal cord

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5
Q

What is the main function of the cerebellum?

A

Ensure that correction of currentmovements to match those intended

(what we want to happen is actually happening)

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6
Q

Most inputs enter the cerebellum via what peduncles?

what are the major inputs to these areas

A

Middle and inferior peduncles.

Cerebral cortex –> pontine – (pontocerebellar tract) –> middle peduncle

Vestibular and cochlear nuclei, inferior olive, dorsalspinocerebellar and cuneocerebellar tracts –> inferior peduncle

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7
Q

Cerebellar lesions cause issues to the ____ [same/opposite] side of the body

A

Cerebellar lesions cause issues to the SAME SIDE of the body

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8
Q

Lesions to the vermis —>

Lesions at the hemispheres –>

A

Lesions to the vermis —> gait or truncal issues

Lesions at the hemispheres –> motor coordination issues on the SAM SIDE

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9
Q

Where are the following cerebellar nucleus located?

Dentate nuc?

Interposed nuc?

Fastigal nuc?

A

Dentate nuc – hemisphere

Interposed nuc – paravermis?

Fastigal nuc – vermis and floculus

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10
Q

Inferior peduncle

Afferent fibers (3)

Efferent

A

Inferior olivary nucleus, vestibular nuclei, spinal cord, (trigeminal and reticular formation ) –> inferior peduncle

Inf. peduncle –> vestibular nuclei

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11
Q

Middle Penducle

Afferent

Efferent

A

cerebral cortex –> middle peduncle

no efferents

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12
Q

Superior Peduncle

afferent

efferent

A

only 1 afferent: anterior spinocerebellar

most efferents, from the deep cerebellar peduncles

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13
Q

Name the 4 major parts of the microscopic anatomy of the cerebellum

A

(top to bottom)

Molecular Layer

Purkinje Cell Layer

Ganular Layer

White Matter

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14
Q

What two cells does the Molecular Layer consist of:

A

basket cells and stellate cells

Basket Cell axons synpase on purkinje cell Body

Stellate cell axons synapse on purkinje dendrites

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15
Q

What is the purkinje cell layer consist of?

A

purkinje cell only axons that leave the cerebellar cortex, predominately output of the cerebllum

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16
Q

What does the granular layer consist of:

A

Granular cells – send their axons into the molecular layer as parallel fibers

17
Q

Climbing fibers:

Originate from ______ and synpase on ______, which ______ [activate/inhibit].

Mossy Fibers:

Originate from ______ and synpase on ______, which ______ [activate/inhibit]

–> synapse on (3) and are ________

Purkinje cells:

Synapse on _______ and are ______ [activate/inhibit].

A

Climbing fibers:

Originate from CONTRALATERAL INFERIOR OLIVE NUCLEUS ONLY and synapse on PURKINJE CELLS, which ACTIVATE [activate/inhibit].

FEW CAN SYNPASE ON MONAY –> LONG-TERM DEPOLARIZATION

Mossy Fibers:

Originate from ALL OTHER LOCATIONS and synpase on GRANULAR CELLS, which ACTIVATE [activate/inhibit]

GRANLAR CELLS–> synapse on: PURKINJE, BASKET AND STELLATE CELLS and are ACTIVATING

Purkinje cells:

Synapse on DEEP CEREBELLAR NUCLEI and are INHIBITORY [activate/inhibit].