Cerebellum

Question 1

Which tract is the only cerebllar tract with afferent fibers into the superior peduncle

Answer 1

Anterior spinocerebellar

Origin: ascends in contralateral spinal cord (t12-L5)

Terminates: vermis and intermediate zone - ipsilateral

Question 2

Which tract is the only cerebellar tract with affarent fibers from the middle peduncle?

Answer 2

Pontocerebellar

Origin: Pontine Nuclei

Termination: ant and post lobes - contralateral and vermis - ipsilateral

Question 3

Major inputs to the cerebellum come in via teh _______ and _______ fibers

Answer 3

Major inputs to the cerebellum come in via the mossy and climbing fibers

Question 4

Major output from the cerebellum are via ______ fibers to the _____ and _____.

The cerebellum ____[does/doesn’t] have direct connection to the spinal cord

Answer 4

Major output from the cerebellum are via purkinje fibers to the thalamus and red nucleus.

The cerebellum DOES NOT have direct connection to the spinal cord

Question 5

What is the main function of the cerebellum?

Answer 5

Ensure that correction of currentmovements to match those intended

(what we want to happen is actually happening)

Question 6

Most inputs enter the cerebellum via what peduncles?

what are the major inputs to these areas

Answer 6

Middle and inferior peduncles.

Cerebral cortex –> pontine – (pontocerebellar tract) –> middle peduncle

Vestibular and cochlear nuclei, inferior olive, dorsalspinocerebellar and cuneocerebellar tracts –> inferior peduncle

Question 7

Cerebellar lesions cause issues to the ____ [same/opposite] side of the body

Answer 7

Cerebellar lesions cause issues to the SAME SIDE of the body

Question 8

Lesions to the vermis —>

Lesions at the hemispheres –>

Answer 8

Lesions to the vermis —> gait or truncal issues

Lesions at the hemispheres –> motor coordination issues on the SAM SIDE

Question 9

Where are the following cerebellar nucleus located?

Dentate nuc?

Interposed nuc?

Fastigal nuc?

Answer 9

Dentate nuc – hemisphere

Interposed nuc – paravermis?

Fastigal nuc – vermis and floculus

Question 10

Inferior peduncle

Afferent fibers (3)

Efferent

Answer 10

Inferior olivary nucleus, vestibular nuclei, spinal cord, (trigeminal and reticular formation ) –> inferior peduncle

Inf. peduncle –> vestibular nuclei

Question 11

Middle Penducle

Afferent

Efferent

Answer 11

cerebral cortex –> middle peduncle

no efferents

Question 12

Superior Peduncle

afferent

efferent

Answer 12

only 1 afferent: anterior spinocerebellar

most efferents, from the deep cerebellar peduncles

Question 13

Name the 4 major parts of the microscopic anatomy of the cerebellum

Answer 13

(top to bottom)

Molecular Layer

Purkinje Cell Layer

Ganular Layer

White Matter

Question 14

What two cells does the Molecular Layer consist of:

Answer 14

basket cells and stellate cells

Basket Cell axons synpase on purkinje cell Body

Stellate cell axons synapse on purkinje dendrites

Question 15

What is the purkinje cell layer consist of?

Answer 15

purkinje cell only axons that leave the cerebellar cortex, predominately output of the cerebllum

Question 16

What does the granular layer consist of:

Answer 16

Granular cells – send their axons into the molecular layer as parallel fibers

Question 17

Climbing fibers:

Originate from ______ and synpase on ______, which ______ [activate/inhibit].

Mossy Fibers:

Originate from ______ and synpase on ______, which ______ [activate/inhibit]

–> synapse on (3) and are ________

Purkinje cells:

Synapse on _______ and are ______ [activate/inhibit].

Answer 17

Climbing fibers:

Originate from CONTRALATERAL INFERIOR OLIVE NUCLEUS ONLY and synapse on PURKINJE CELLS, which ACTIVATE [activate/inhibit].

FEW CAN SYNPASE ON MONAY –> LONG-TERM DEPOLARIZATION

Mossy Fibers:

Originate from ALL OTHER LOCATIONS and synpase on GRANULAR CELLS, which ACTIVATE [activate/inhibit]

GRANLAR CELLS–> synapse on: PURKINJE, BASKET AND STELLATE CELLS and are ACTIVATING

Purkinje cells:

Synapse on DEEP CEREBELLAR NUCLEI and are INHIBITORY [activate/inhibit].