Cephalosporins Flashcards
1
Q
Give an example
A
Cephradine, cefuroxime
2
Q
What are the indications for use
A
- Infection due to sensitive gram +ve + gram -ve bacteria
3
Q
What are the side effects
A
RARE
- Abx ass colitis
- Serum sickness like reactions w/rash, fever, arthralgia, anaphylaxis, urticaria, SJS/TEN, deranged LFTs, transient hepatitis, eosinophilia
- Blood disorders
- Dizziness
- Sleep disturbance
4
Q
What are the interactions
A
- AMINOGLYCOSIDES (inc risk nephrotoxicity)
- COUMARINS (enhance anticoag effect)
