Central Nervous System drugs

Question 1

It can be defined as the study of drugs that alter processes controlled by the nervous system.

Answer 1

Neuropharmacology

Question 2

There are two basic step in the process by which the neuron influences the behavior of the postsynaptic cell.

Answer 2

axonal conduction and synaptic transmission

Question 3

It is simply the process of conducting an action potential down the axon of the neuron.

Answer 3

Axonal conduction

Question 4

It is the process by which information is carried across the gap between the neuron and the postsynaptic cell.

Answer 4

Synaptic transmission

Question 5

This concept is central to understanding the actions of neuropharmacologic drugs.

Answer 5

The impact of a drug on a neuronally regulated process is dependent on the ability of that drug to directly or indirectly influence receptor activity on target cells.

Question 6

Steps in synaptic transmission.

Answer 6

Step 1. Synthesis of transmitter
Step 2. Storage of transmitter in vesicles
Step 3. Release of transmitter
Step 4. Receptor binding
Step 5. Termination of transmission

Question 7

An effect on receptor function equivalent to that produced by the natural neurotransmitter at a particular synapse

Answer 7

activation

Question 8

A drug whose effects mimic the effects of a natural transmitter would be said to

a. increase receptor activation
b. decrease receptor activation

Answer 8

increase receptor activation

Question 9

A drug whose effects were equivalent to reducing the amount of natural transmitter available for receptor binding would be said to

a. increase receptor activation
b. decrease receptor activation

Answer 9

decrease receptor activation

Question 10

There are three different effects that drugs are known to have on transmitter synthesis. They can:

Answer 10

(1) increase transmitter synthesis
(2) decrease transmitter synthesis, or
(3) cause the synthesis of transmitter molecules that are more effective than the natural transmitter itself.

Question 11

It refers to the unique anatomy of capillaries in the CNS.

Answer 11

blood-brain barrier (BBB)

Question 12

It encompasses all drug groups that have an effect on the neuroconduction of the brain and spinal cord.

Answer 12

Pharmacology of central nervous system (CNS)

Question 13

Used for psychiatric disorders, suppression of seizures, relief of pain, production of anesthesia

Answer 13

Central nervous system drugs

Question 14

It is a decreased response occurring in the course of prolonged drug use

Answer 14

Tolerance

Question 15

It is a state in which abrupt discontinuation of drug use will precipitate a withdrawal syndrome

Answer 15

Physical Dependence

Question 16

A type of drug that increases the levels of certain chemicals in the brain and increases alertness, attention, energy, and physical activity. It also raise blood pressure and increase heart rate and breathing rate.

Answer 16

CNS stimulants

Question 17

It is a strong central nervous system stimulant. People with some conditions, including ADHD, take them as medication.

Answer 17

Amphetamine

Question 18

Drugs that directly/ indirectly cause activation of dopamine receptors. This type of drugs are deployed with person with Parkinson’s disease.

Answer 18

Dopaminergic drugs

Question 19

Drugs that relaxes the skeletal muscles by disrupting the transmission of nerve impulses at the motor end plate

Answer 19

Neuromuscular blocking drugs

Question 20

This drug is used in addition to anesthesia to cause skeletal muscle relaxation. It functions as competitive antagonists.

Answer 20

Non-depolarizing blocking agents