Autonomic Nervous System drugs Flashcards
It regulates the body’s involuntary functions, including heart rate, respiratory rate, and digestion.
Autonomic nervous system
The autonomic nervous system works through a balance of its two main components. They are:
sympathetic and parasympathetic nervous systems
The nervous system has two main divisions of:
Central nervous system and peripheral nervous system
The peripheral nervous system has two major subdivisions:
1) the somatic motor system
2) the autonomic nervous system
The autonomic nervous system has three principal functions. These regulatory activities are shared between the sympathetic and parasympathetic divisions of the autonomic nervous system.
(1) regulation of the heart
(2) regulation of secretory glands (salivary, gastric, sweat, and bronchial glands)
(3) regulation of smooth muscles (muscles of the bronchi, blood vessels, urogenital system, and GI tract).
parasympathetic nervous system is concerned primarily with what might be called the…
“housekeeping” chores of the body (digestion of food and excretion of wastes).
The anatomy of the parasympathetic nervous system offers two general sites at which drugs can act:
(1) the synapses between preganglionic neurons and postganglionic neurons and (2) the junctions between postganglionic neurons and their effector organs.
The drugs that affect the sympathetic nervous system have two general sites of action:
(1) the synapses between preganglionic and postganglionic neurons (including the adrenal medulla)
(2) the junctions between postganglionic neurons and their effector organs
The neurons that go from the spinal cord to the parasympathetic ganglia are called
preganglionic neurons
The neurons that go from the ganglia to effector organs are called
postganglionic neurons
They are receptors that sense blood pressure. This reflex is important to us because it frequently opposes our attempts to modify blood pressure with drugs.
Baroreceptors
It is the steady, day-to-day influence exerted by the autonomic nervous system on a particular organ or organ system. It provides a basal level of control over which reflex regulation is superimposed.
Autonomic tone
It sends impulses to the CNS
Afferent
It receives impulses, transmits through the spinal cord to effector organ cells
Efferent
Within autonomic pharmacology, there are four specific categories of drugs based on how they affect the ANS:
- adrenergic agonist
- adrenergic antagonist
- cholinergic agonist
- cholinergic antagonist