centenarians Flashcards
what is a centenarian?
a person who lives to or beyond the age of 100 years.
the term centenarian is associated with ___________.
longevity
super-centenarian?
a person who has lived to the age of 110 or more,
super centenarian is something only achieved by _____ in 1,000 centenarian.
1
according to recent estimate how much proportion of us population is centenarian?
10-20 centenarians per 100,000 population in us
who is the oldest validated Canadian ever? and what did she claimed as key to longevity.
Marie-Louise Meilleur(118 yrs)
1880-1998
hard work = key to longevity.
name the French supercentenarian from arles?
Jeanne Calment , passed away in 122 years and 164 days in 1997
health and lifestyle routines of Jeanne calment
took care of her skin with olive oil and puff powder
cycling until 100 bday
gymnastic on wheelchair, flexing stretching
washed herself with flannel cloth rather than shower
mad herself fruit salads
consistent routine
went to bed early, woke up early
what was the age of the man in bigger Saskatchewan who was a centenarian and what was his lifestyle
107, 4 bottles red wine almost every day
how many centenarians in 2011 did Canada, Japan, Russia and (France,italy,uk) had per 100,000
canada- 17.4
Japan- 37
russia- 4
France, Italy and uk- higher centenarian rates than Canada
what was the life expectancy in 1920s and 2000-2002?
1920s- male-59 yrs
females-61 yrs
2000-2002- male-77 yrs
females-82 yrs
how many centenarians were there in Canada during 2001
3795
how many centenarians in Canada in 2022?
13,484
what was Canada’s population in 2011 compared to 1911
1911- 7.2 million
2011-33.5 million
when could have the 2011 centenarians be born and started life?
born in 1911 or before,
children during ww1,
entered labour force, started family in great depression 1930s,
older adults during baby boom period, retired in 70s
what year was the Great Depression
1930s
baby boom period?
1946-1965
centenarians present in Canada from 2018-2022 according to statistics?
2018-9,457
2019-10,581
2020-11,815
2021-12,906
2022-13,484
which province had the highest life expectancy during 20the century and finally the highest. no. of centenarians?
Saskatchewan, 31 per 100,000 in 2011.
the lowest no. of centenarians according to statistics 2011?
3 terr- Yukon, northwest territories, Nunavut (4.7 Per 100,000)
average centenarians in Canada during 2011 statistics?
17.4 per 100,000
current trend in ______ in us is affecting life longevity.
obesity
if ________ rates continue to decline in the next decade the number of people belonging to 2011 and reaching 100 in 2111 is much higher.
mortality rates
diff life expectancies in statistics show ________ of life expectancy.
variations
what were the 2 blips caused in life expectancy?
2017- opioid pandemic
2020- covid 19
what blip affected 2019 cohort?
2017- opioid pandemic
who reach the age of 100 more? men/women
women
2011 census counted ______ women and ______ men as centenarians and the corresponding sex ratio was ___ women for every 100 men?
4,870 women and 955 men
500 women per 100 men
in Canadian population up to the age of 26, more ___ were present and after that more ______.
upto 26- men
after 26- women
by age 65 in Canada their were _____ women for 100 men and by age 80 _____ many women for 100 men
125
170
what is a fountain of youth
a spring that supposedly restores the health of anyone who drinks or bathes in its waters.
__________, a spanish explorer was looking for fountain of youth aka ________ to cure his_______ but discovered _______ in _______
Ponce de león
waters of Bimini
aging
florida
1513
factors to living to be 100?
1.inherited genes or your own biology
2.where you live
3.the choices you make
4.eating a plant based diet, quitting smoking, reducing stress, exercising, and getting enough sleep. Drinking coffee or tea, practicing conscientiousness, finding joy, and limiting your alcohol intake also benefit your long-term health and well-being.
what is a “blue zone”?
an area characterized by extreme longevity in the sardinia island.
highest concentration of male centenarians
who introduced blue zone?
Michel Poulain and Giovanni pes
what does the diff lifestyle o people in blue some include?
regular low level activity
plant-prioritized diet
eat until 80% full
intergenerational family
strong friendship structure
reason for waking up in the morning
pause for nature 24 hours 1 per week
what are the 9 common diets told by dan buettner to live 100+ after studying blue zone community?
1.move naturally(no exercise but perform such activity no need of exercise just physical movement0
2.right outlook(sense of purpose)ikigai
3.eat wisely(plant, 80%rule)
4.connection with loved ones, belong, right tribe
family, not smoking, plant-slant diet, constant moderate physical activity, social engagement, legumes.
what are the common longevity myths told by dan buettner?
1.if I try really hard, can live upto 100.
2.treatments exist that can slow aging.
do sibling of centenarians live longer as well?
potential genetic traits of longevity
97th percentile-95+
what are some researched longevity ideas?
1.genetic immunological diff 🧬
2. genetic influence on insulin regulation
3.calorie restricted diet-works in rodents
what are the benefits of calorie restricted diet in human?
beneficial effects against obesity, insulin resistance, inflammation, oxidative stress, left ventricular diastolic dysfunction, reduced cholesterol, blood pressure, and risk factors for cardiovascular disease. Including: Yeast, worm, fruit fly, rodent, primate
how did 30%dietary restriction affect n adult 20 yr old rhesus monkey?
1.reduced age related death(66)
2.incidence of neoplasia and cardiovascular disease was 50%lower
3.none developed diabetes or pre diabetes
4.major reduction in body fat mass
5.higher insulin sensitivity
6.reduced inflammation and oxidative damage
(4,5,6 also noticed in rodents)
7.immune senescence, sarcopenia and brain atrophy of grey matter were reduced
what are some possible downsides of dietary restriction?
reduced resistance to infection or reduced affect of wound healing
what were the adaptions observed in dietary restricted rodents?
major reduction In body fat mass, higher insulin sensitivity, reduced inflammation and oxidative damage
what hormonal adaptations observed in dietary-restricted rodents are seen in humans?
increased adiponectin, reduction in triiodothyronine, testosterone and insulin
dietary restriction reduced the ____________ of the carotid arteries which is a risk factor for cardiovascular disease.
intimal-media thickness
what effect does extreme dietary restriction has on one’s health?
amenorrhea, infertility, sarcopenia, osteoporosis, and immune deficiencies
______, the TOR inhibitor extends the mouse life span is an ______ for human and may not prove good for human health.
rapamycin
immunosuppressant
genetic deletion of the ________ or of the downstream_______ in mice extends life span and induces a broad-spectrum improvement in health
GH receptor
S6 Kinase
