Cellulitis / Staph aureus Flashcards

1
Q

Possible microbes?

A

Staph aureus
Strep pyogenes

All gram positive cocci

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2
Q

Treatment?

A

Flucloxacillin

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3
Q

Virulence factors?

A

Coagulase - localised clotting - restricts access

FnBP - adherence - mucosa

Haemolysis

Superantigen exotoxins - high affinity T cell receptor - lots of cytokines related

Protein A - anti-phagocytic - anti-opsonins effect binds IgG

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4
Q

Skin infections from staph aureus?

A

Cellulitis
Abscess
Folliculitis (most common)

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5
Q

Staph aureus toxinoses?

A

Toxic shock syndrome

Scalded skin syndrome

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6
Q

Other staph aureus related conditions?

A

Acute/ chronic osteomyelitis

Acute endocarditis

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7
Q

Treatment for MRSA?

A

Vancomycin

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