Cellular Respiration Flashcards

1
Q

what is the order of the cellular respiration stage

A

glycolysis
pyruvate oxidation
krebs cycle
oxidative phosphorylation/ ETC

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2
Q

how/where does hexokinase help

A

happens in cytoplasm
aids in the phosphorylation of glucose to form glucode 6 phosphate
ATP to ADP

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3
Q

how/where does phosphoglucose isomerse

A

cytoplasm

the isomerisation of glucose-6-phosphate to fructose-6-phosphate

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4
Q

how/where does phosphofructokinase aid

A

cyctoplasm

the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate

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5
Q

how/where does aldolase aid

A

cyctoplasm

separates fructose-1,6-biphosphate to G3P

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6
Q

how/where does G3P dehydrogenase aid

A

cytoplasm

uses NAD to NADH to form BPG

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7
Q

how/where does phosphoglycerate kinase aid

A

cytoplasm

changes 3PG to 2PG

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8
Q

how/where does enolase aid

A

cytoplasm

changes 2PG to pep

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9
Q

how/where does pyruvate kinase aid

A

cytoplasm

dephosphorylation of pep to form ATP and making a pyruvate

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10
Q

what is the net gain of glycolysis

A

2 pyruvate
2 ATP
2 NADH

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11
Q

what is the net gain of the krebs cycle

A

2 ATP
3 NADH
2 FADH2

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12
Q

how much ATP is formed through ETC

A

34

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13
Q

what is the first complex for ETC

A

NADH dehydrogenase

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14
Q

what and where does NADH dehydrogenase do

A

mitochondrial membrane

NADH to NAD releasing an H+

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15
Q

what/where does the cyctochrome complex happen

A

mitochondrial membrane

FADH2 to FAD releasing H+

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16
Q

what is the second complex in ETC

A

cyctochrome complex

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17
Q

what is the third complex in ETC

A

BC1 Complex

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18
Q

what is the fourth complex in ETC

A

cytochrome oxidase complex

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19
Q

what/where does the BC1 complex aid

A

mitochondrial membrane

aids in pumping electrons through to the cyctochrome oxidase complex

20
Q

what/where does the cytochrome oxidase do

A

mitochondrial membrane

uses electrons from BC1 complex, adds it to O2 to make water

21
Q

what does the ATP-ase complex do

A

it drives all the protons from the inner membrane space down to the matrix thanks to the electrochemical gradient… does some stuff and adds H+ to ADP to make ATP but many many times… 34 to be exact

22
Q

what happens if there is no O2 for ETC

A

it gets backlogged and closes up

23
Q

what happens if there’s no food for ETC

A

no electrons in the first place- literally doesn’t do anything at all

24
Q

how is lactic acid formed

A

when there isn’t enough oxygen when exercising for all the glucose being used, NADH transfers their H+ atoms to pyruvate

25
what does lactic acid do
causes stiffness, soreness and fatigue
26
what happens to lactic acid after it is no longer needed
transported to the liver and oxidized back into pyruvate
27
why do we breathe heavily after working out
- not enough oxygen to keep up with the glucose (think complex IV) - instead, after glycolysis, the NADH wont dephosphorilize at complex 1 and will instead be sent to phosphorilize pyruvate forming lactase - if the pyruvate that is straight out of glycolysis is being phosphorilated right away, there will be no acetyl CoA for the krebs cycle, and it will stop - so glycolysis is needed to produce ATP, it needs 2 NAD+ to occur, so it will oxidise NADH with built up pyruvate as the oxidising agent creating lactase - the lactic acid buildup throws off the pH making it sore, tired, or stiff - at the end it needs to be dephosphorilated back into pyruvate, which takes oxygen... hence why we breathe more
28
explain glycolysis
im not typing it out go look it up or smth idk
29
what are the first four substances in krebs cycle
acetly CoA oxoloacetate citrate isocitrate
30
what are the 3 reactions that occur in pyruvate oxidation
1. loses CO2 2. NAD+ to NADH 3. joins CoA to form acetyl CoA
31
what happens if cyanide inhibits cytochrome oxidase
Electrons get clogged up (E.T.C. is blocked) Oxygen cannot accept final electrons ATP production is shut down, leading to coma and death
32
what are the metabolic checkpoints/ regulators in CR
I DONT KNOW ASK HILLARY OR KEVIN OR SMTH
33
what is the order of all the phosphorylations in krebs cycle
``` acetyle CoA to Oxoloacetate to Citrate to Isocitrate *lose co2* NAD+ to NADH *lose co2* NAD+ to NADH ADP to ATP FAD to FADH2 *CoA leaves* *h2o goes in* NAD+ to NADH ```
34
What is ATP composed of
Nitrous base 5 carbon sugar 3 phosphate groups Large amounts of free energy
35
What is catabolism
Energy out as bonds are broken
36
What is anabolism
Energy in as bonds are broken
37
What are phototrophs
Organisms that build organic compounds from simpler inorganic compounds using light (like plants)
38
What are heterotrophs
Rely on autotrophs for food (energy)
39
What are chemoautotrophs
Gain energy from inorganic materials use of light (found in extreme environments)
40
How long does it take for a cell to die without oxygen
5 mind
41
What does an excess of ATP do
Inhibits phosphofructokinase
42
What does an excess of citrate do
Inhibits phosphofructokinase
43
What does an excess of NADH from the krebs cycle do
Inhibits pyruvate dehydrogenase
44
What does an excess of ADP do
Activates phosphofructokinase
45
how many ATP for NADH
3 ATP for 1 NADH
46
how much ATP formed for 1 FADH2
2ATP for FADH2