Cellular Repsonse To Stress

Question 1

Hyperplasia in breast is due to

Answer 1

Estrogen ( not during pregnancy / lactation)

Question 2

Hyperplasia in thyroid = thyroid goiter why?

Answer 2

Due to decreased dietary iodine —> can’t make thyroid hormone

Question 3

Pyknosis

Answer 3

Nucleus shrinks and increased basophilia and dna condensed into solid shrunken mass

Question 4

Karyorrehexis

Answer 4

Nucleus fragmentation

Question 5

Karyolysis

Answer 5

Nucleus disappears because of DNase

Question 6

Coagulative necrosis

Answer 6

Cyto denatured 
Hypoxia 
Kidneys and heart 
Architecture of cells preserved 
Denatured proteins

Question 7

Liquefactive necrosis

Answer 7

Hydrolyzed cyto
Bacterial infections 
In brain 
Creamy yellow liquid mass 
Results from release of protéolytique enzymes

Question 8

Caseous necrosis

Answer 8

Hydrolyzed cyto 
TB and fungi
In lymph nodes 
Cheesy yellow to white appearance 
Results from granulmatous inflammation

Question 9

Enzymatic fat necrosis

Answer 9

Saponified
Lipase
Occurs in pancreas
Results from lipase which release FFA saponification —> FfAs and calcium binding —> salts ( white substance)

Question 10

Gangerous necrosis

Answer 10

Coagulatrice bc of loss of blood supply and superimposed bacterial infection

Modified by liquefactive action of bacteria —> attract leukocytes —> wet gangrene

Question 11

What gene regulates apoptosis ?

Answer 11

p53