CellSig1 - 10

Question 1

Define signal transduction

Answer 1

Process by which EC signalling molevules cause changes in target cells

Question 2

7 types of signal

Answer 2

Proteins, small peptides, amino acids, nucleotides, steroids, fatty acid derivatives, dissolved gases

Question 3

Define paracrine signalling

Answer 3

Local signalling

Question 4

Define autocrine signalling

Answer 4

Signalling to itself, or same tissue

Question 5

What kind of molecules can signal by gap junction signalling?

Answer 5

Small molecules such as cAMP and Ca2+

Question 6

What are gap junctions made from?

Answer 6

6 connexins in each membrane (2 connexons of 6 connexins)

Question 7

Describe a gap junction with mixed connexins

Answer 7

Heterotypic

Question 8

Describe a gap junciton with all the same connexins

Answer 8

Homotypic

Question 9

What characterises endocrine signalling?

Answer 9

Slow, low concentrations, high affinity receptors

Question 10

What characterises synaptic signalling?

Answer 10

Fast, high concentrations, low affinity receptors