Cells part 2 Flashcards
How does the skin act as a defence in the body
- acts as a protective barrier to pathogens. dead skin cells layer stops pathogens from piercing through
- oily sebum covers the skin. creates a slightly acidic layer that prevents growth of harmful bacteria
- harmless micros on skin surface, compete with pathogens for resources prevents their growth
How are the breathing and digestive systems adapted to act as a defence ?
- lined with a mucous membrane which secretes mucous and traps microorganisms
- can then be destroyed by WBC called phagocytes
- mucus also contains lysozyme which destroys bacteria by breaking down cell wall ( also found in tears)
How is the stomach adapted for defence against pathogens ?
- mucus in stomach contains hydrochloric acid, helps to kill pathogens in food or water
What are expulsive reflexes ?
body tries to expel pathogen that has entered body ie through sneezing, coughing, blowing nose, vomiting etc
What are the two main types of phagocytes ?
macrophages and neutrophils
What are antigens
chemicals on the surface of cells which allow us to recognise them. foreign antigens are found on pathogens., so the body wouldn’t recognize these, and thus go for attack.
What are opsonins ?
special molecules which recognise the foreign chemicals and stick to them. tag pathogen as foreign
What are neutrophils
- phagocyte and granulocyte. involved in allergy response - release histamine
What are macrophages
phagocytes and antigen-presenting cells which are derived from monocytes. Long-lived immune cells
What is a granulocyte?
type of WBC which contains protein granules
Phagocytes act as what
non specific defence in body
Lymphocytes act as what
specific defence because they release antibodies and antitoxins which are complement to antigens found on pathogen surface
Describe the role of phagocytes ( neutrophil) in breaking down pathogen
- phagocytes such as neutrophils attracted to molecules produced by pathogens. moves towards pathogen
- receptors on membrane attach to opsonins, phagocytes engulfs pathogen. pathogens now engulfed into phagosome
- lysosomes move towards phagosome and fuse with it to form lysophagosome.-
- lysosomal enzymes now break down the pathogen and destroy it.