Cells of the immune system

Question 1

Three major classifications of lymphocytes

Answer 1

B cells, T cells, natural killer (NK) cells

Question 2

Precursors of all lymphocytes originate where?

Answer 2

Bone marrow

Question 3

Where do B cells mature?

Answer 3

Bone marrow

Question 4

Where do T cells mature?

Answer 4

Thymus

Question 5

Which are the main functional cells of the lymphatic or immune system?

Answer 5

Lymphocytes

Question 6

T cells: humoral or cell-mediated immunity?

Answer 6

Cellular immunity

Question 7

B cells: humoral or cell-mediated immunity?

Answer 7

Humoral immunity

Question 8

Lymphocyte that produces circulating antibodies

Answer 8

Plasma cells

Question 9

Which organ will take over in case of a bone marrow dysfunction?

a. Lungs
b. Kidney
c. Spleen
d. Yolk

Answer 9

c

Question 10

A viral infection will lead to a rise in what type of cell?

a. Eosinophil
b. Monocyte
c. Neutrophil
d. Lymphocyte

Answer 10

d

Question 11

Which characterizes a the red blood cell of an anemic patient?

a. hypochromic and microcytic
b. hypochromic and macrocytic
c. hyperchromic and microcytic
d. hyperchromic and macrocytic

Answer 11

a

Question 12

The two common blood lines in the normal bone marrow?

a. Erythropoiesis and megakaryopoiesis
b. Erythropoiesis and granulopoiesis
c. Megakaryopoiesis and granulopoiesis
d. Megakaryopoiesis alone

Answer 12

b

Question 13

The following characterizes a platelet?

a. biconvex shape
b. composed of middle hyalomere and peripheral granulomere
c. central microtubule ring

Answer 13

a

Question 14

Which does not characterize changes that happen during erythropoiesis?

a. formation of granules?
b. gradual loss of ribosomes
c. decrease in size
d. cytoplasm becomes eosinophilic

Answer 14

a

Question 15

Which of the following is not granule forming?

a. red blood cell
b. neutrophil
c. lymphocyte
d. eosinophil

Answer 15

a

Question 16

Which of the following is not stored in blood banks?

a. RBC
b. WBC
c. Platelet
d. Plasma

Answer 16

b

Question 17

Which of the following has the greatest proportion in blood?

a. RBC
b. WBC
c. Platelet
d. cybersex

Answer 17

a

Question 18

Which ABO blood type contains the most antibodies in the plasma?

a. A
b. B
c. AB
d. O

Answer 18

d

Question 19

Which site is most accessible to perform bone marrow biopsy in an adult?

a. Skull
b. Distal humerus
c. Ribs
d. Pelvis

Answer 19

d

Question 20

Antibodies on the B-lymphocyte

Answer 20

IgM, IgD

Question 21

Type of MHC in B-lymphocytes

Answer 21

Type II

Question 22

When a B-lymphocyte is activated, which type of cells does it become?

Answer 22

Memory cells and effector cells (plasma cells)

Question 23

Two ways of activating the B-lymphocyte

Answer 23

By the binding of an antigen, and by T-helper cells activation

Question 24

Lymphocyte with CD4+ marker

Answer 24

T helper cells

Question 25

Lymphocyte with CD8+ marker

Answer 25

T cytotoxic cells

Question 26

Two types of T lymphocytes

Answer 26

T-helper and T-cytotoxic cells

Question 27

Which lymphocyte secretes cytokines?

Answer 27

T-helper cells

Question 28

MHC II is recognized by which lymphocyte?

Answer 28

T-helper cells

Question 29

MHC I is recognized by which lymphocyte?

Answer 29

T-cytotoxic cells

Question 30

Which lymphocyte activates B-cells?

Answer 30

Helper T cells

Question 31

Which is TRUE of the neutrophil? A. Large storage pool in both the peripheral blood and bone marrow B. Decreased in parasitic infestations C. Phagocytosis of senescent organelles D. Principal cell in the cell-mediated immune response

Answer 31

A

Question 32

Which is NOT a phagocytic cell? A. Macrophage B. Neutrophil C. Eosinophil D. Basophil

Answer 32

D

Question 33

Which is the longest-lived blood cell? A. RBC B. Monocyte C. Basophil D. Lymphocyte

Answer 33

D

Question 34

Which is a normal differential WBC count? A. N=30%; L=60%; M=5%, E=2%, B=0.5% B. N=60%: L=30%; M=0.5%; E=2%; B=5% C. N=30%; L=60%; M=5%; E=0.5%, B=2% D. N=60%; L=30%; M=5%, E=2%, B=0.5%

Answer 34

D

Question 35

What does an increased reticulocyte count mean? A. Incubating bacterial infection B. Recovery from anemia C. Bone marrow failure D. Chronic renal failure

Answer 35

B

Question 36

Which bone marrow cells are capable of mitosis, but NOT self-renewal? A. Pluripotential stem cells B. Progenitor cells C. Precursor cells D. Mature cells

Answer 36

C

Question 37

Why are the pluripotential stem cells in the bone marrow spared by anti-proliferative chemotherapeutic drugs? A. Very few in number B. Low mitotic activity C. Self-renewing D. Being undifferentiated

Answer 37

B

Question 38

Which blood cell lineage does NOT form cytoplasmic granules? A. Erythropoeisis B. Granulopoeisis C. Megakaryopoeisis D. Monopoeisis

Answer 38

A

Question 39

Which may benefit a patient with chronic renal failure? A. Monocyte colony stimulating factor (M-CSF) B. Erythropoietin C. Interleukin-3 (IL-3) D. Granulocyte colony stimulating factor (G- CSF)

Answer 39

B

Question 40

Which CORRECTLY describes the composition of blood, by volume? A. RBC > plasma > WBC B. Plasma > RBC > WBC C. Plasma > WBC > RBC D. RBC > WBC > plasma

Answer 40

B

Question 41

Which serves as a bridge that anchors the cytoskeleton to the RBC membrane giving it flexibility and resilience? A. Spectrin B. Actin C. Ankyrin D. Rh protein

Answer 41

C

Question 42

Which is the reason why Type O is considered the universal donor for packed RBC transfusions? A. It does not have A nor B antigens. B. It does not have anti-A nor anti-B antibodies. C. It has both anti-A and anti-B antibodies. D. It has both A and B antigens.

Answer 42

A

Question 43

Which condition may give rise to a macrocytic type of anemia? A. Iron-deficiency B. Sickle cell disease C. Vitamin B12 deficiency D. Hereditary spherocytosis

Answer 43

C

Question 44

Which is the last nucleated cell in the erythropoeitic line? A. Orthochromatophilic erythroblast B. Basophilic erythroblast C. Proerythroblast D. Polychromatophilic erythroblast

Answer 44

A

Question 45

Which blood component is NOT used as a therapeutic product? A. Platelets B. Plasma clotting factors C. Plasma immunoglobulins D. White blood cells

Answer 45

D

Question 46

Which is elevated in the peripheral blood of a patient with allergy? A. Basophil B. Mast cell C. Eosinophil D. Neutrophil

Answer 46

C

Question 47

Which cell gives rise to all blood cells?

Answer 47

Hemopoetic stem cell or Pluripotent stem cell

Question 48

The hemopoetic stem cell gives rise to these two cell lineages

Answer 48

Myeloid line and Lymphoid line

Question 49

Which RBC precursor is the first recognizable though not easily identifiable in slides?

Answer 49

Proerythroblast

Question 50

RBC precursor with checkered board pattern in the nucleus

Answer 50

Polychromatiphilic erythroblast

Question 51

First RBC precursor no longer capable of mitosis

Answer 51

Orthochromatophilic erythroblast (normoblast)

Question 52

RBC precursor without a nucleus

Answer 52

Polychromatophilic erythrocyte (reticulocyte)

Question 53

Immediate precursor of platelets

Answer 53

Megakaryocytes

Question 54

First distinguishable precursor of granulocytes

Answer 54

Myeloblast

Question 55

Precursor of granulocytes in which specific granules begin to appear

Answer 55

Myelocyte

Question 56

Granulocyte precursor where eosinophils, basophils and neutrophils begin to be distinguishable

Answer 56

Metamyelocyte

Question 57

Granulocytes

Answer 57

Eosinophil, basophil, neutrophil

Question 58

Agranulocyte

Answer 58

Monocyte, Lymphocytes