Cells of the Blood Flashcards
1
Q
Where are all blood cells derived from?
A
One common progenitor cell in the bone marrow - the multi potential haematopoietic stem cells (can produce different types of cells)
2
Q
What are the 2 major lineages?
A
Myeloid and lymphoid
3
Q
How many different types of blood do these lineages produce?
A
11
4
Q
What % of blood volume does plasma form?
A
55%
5
Q
How is plasma separated?
A
Centrifugation
6
Q
During the collection of plasma, what is an essential feature of collecting tube?
A
Anticoagulant - prevents clotting by chelating calcium in blood
7
Q
What are the 3 most abundant blood plasma proteins?
A
Albumin
Immunoglobulins
Fibrinogen
8
Q
How is serum different to plasma?
A
Blood is allowed to clot before it is centrifuged
Serum = Plasma - Clotting Factors Plasma = Serum + Clotting Factors (+ clotting inhibitor)