cells, matrix, ossification, bone density, bone variation Flashcards

1
Q

what are the four basic tissues of the human body?

A

epithelial, muscle, neural and connective tissues

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2
Q

what is the function of each type of bone cell?

A

osteoblast - form bones; osteocyte - maintain or nurture bone; osteoclast - remodel bone

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3
Q

what is the primary constituent of the ground substance?

A

glycosaminoglycans

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4
Q

what is the principal type of protein fiber in bone?

A

collagen type I

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5
Q

what is the most frequently described deposit in bone?

A

hydroxyapatite

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6
Q

what is Wolff’s law as it pertains to bone?

A

living tissue will respond to stressors; bone is formed or absorbed in response to stress

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7
Q

what are the three responses of bone that allow it to be described as “living”?

A

it has the ability to heal, to remodel under stressors and to age

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8
Q

what is bone the embryological derivative of?

A

mesenchyme or cartilage

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9
Q

what is the name given to the pattern of ossification in mesenchyme?

A

intramembranous ossification

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10
Q

what is the timing for the appearance of intramembranous ossification?

A

from the second to third month in utero

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11
Q

what is the timing for the appearance of ossification in cartilage?

A

from the second to fifth month in utero

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12
Q

what part of the skull is derived from endochondral ossification?

A

chondrocranium

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13
Q

which bone of the appendicular skeleton is formed by both endochondral and intramembranous ossification?

A

clavicle

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14
Q

what are the primary sources of variation observed in bone?

A

sexual dimorphism (gender variation), ontogenetic variation (growth or age variation), geographic or population-based variation (ethnic variation) and idiosyncratic variation (individual variation)

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