Cells And Tissues Flashcards
Where are ribosomes formed
Nucleolus
What is the cell membrane ?
What is its function?
Phospholipid bilayer with proteins
Retains chemicals in cell and creates cell boundary
Communication
Monitors substances in and out the cell
Which type of cell has larger ribosomes ?
Eukaryotic
What are the functions of the rough endoplasmic reticulum ?
Protein production :
Lysosomal enzymes
Secreted proteins
Integral membrane proteins
What are the functions of the smooth endoplasmic reticulum ?
Lipid production In liver - glycogen to glucose In adrenal medulla - steroid hormone production In muscle - calcium storage Detoxifying into water soluable products
Functions of the Golgi apparatus
Protein modification
Storage of proteins
Packaging of proteins
What are vacuoles
Single membrane storage areas
Made via the fusion of many vesicles
What are vesicles
Much smaller deal with transport of molecules in and out of the cell
What are lysosomes and what do they do ?
Large vesicles
Contain hydrologic enzymes
Extra cellular breakdown of materials - phagocytosis
What makes up the cytoskeleton ?
What is the function ?
Microtubules, intermediate filaments, micro filaments
Maintain cells shape, cell movement, organelle movement, movement of chromosomes
What are the phases of the cell cycle (in order) and what occurs in them ?
G0: terminally differentiated cells G1: cells differentiate and perform functions S: nuclear Dna replication G2: cells prepare for mitotic devision M: mitosis occurs
What are the stages of mitosis and what occurs ?
Prophase - chromosomes visible, shorten, no nucleolus
Metaphase - chromosomes align in centre
Anaphase - chromatids to opposite poles
Telophase - chromatid - chromosome, envelope forms
Cytokinesis - cytoplasmic division
What are the 4 types of tissues ?
Nervous
Epithelial
Muscle
Connective
What can cause changes to tissues ?
Stress - physical and chemical Infection Poor diet Genetic / congenital Degenerative , neoplasms
What is the limit of resolution for the eye ?
What is the limit for a microscope ?
Eye - 0.2mm
Microscope - 0.2 micrometers
What are the stages in tissue preparation ?
Fixation Dehydration Embedding Sectioning Staining
What are the characteristics of epithelial ?
Highly cellular
Very little extra cellular matrix
Cells bind via adhesions/ junctions
Avascular - avoids blood loss !
What is epithelial tissue at risk of ?
At risk of abnormal growth and tumours when regenerating as most common in areas of wear and tear
What are the sides of epithelial cells called ?
Free apical surface
Lateral surfaces
Basal surface
What are microvilli ?
What are the functions ?
Cytoplasmic protrusions
Increases surface area for absorption
What are cillia ?
Where are they found ?
Motile hair like projections
Beat in coordinated movements to move substances
Found in respiratory epithelium
What are stereocilla ?
Where are they found ?
Non motile longer projections
Limited
Only In sensory hair cells of inner ear - epididymis / vas deferens
Increase surface area for absorption
Disease associated with epithelial ? Specifically oral mucosa
Apthalous ulceration
Common in 20% of population
Caused by local trauma or deficiencies in iron/ vit b12
What type of epithelium if found in lining blood vessels, heart , alveoli
Simple squamous
What type of epithelium is found in glands, some ducts, bronchioles and stomach ?
Simple columnar
What type of epithelium is found in the skin ? And the mouth larynx oesophagus ?
Skin - keratinised stratified squamous
Rest - non keratinised stratified squamous
What epithelium is found in salivary gland ducts, sweat glands and ovarian follicle cells (rare)
Stratified cuboidal
What are the functions of simple squamous ?
Diffusion , filtration absorption
Little barrier against friction
What is the function of simple columnar ?
Some have cillia so movement of substances, absorption, secretion
Offers more protection
What is the function of stratified squamous ?
Protection against friction , barrier to infection, reduction of water loss
What is the function of stratified cuboidal ?
Secretion , absorption, protection against infection
What is the function of psuedostratified columnar ?
Almost always ciliated
Synthesise and secrete mucous, movement of mucous
What epithelium is found in the lining of nasal cavity, pharynx, bronchi, trachea ?
Psuedostratified ciliated columnar
What special type of epithelium lines the bladder?
Why is is special ?
Transitional epithelium
Changes to accommodate great stretch and recoil with no damage to cells