Cells and Organs Of The Immune System Flashcards

0
Q

Two types of T helper cells:

A

TH1 cells help the CD8+pre-cytotoxic cells.

TH2 cells help B cells

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1
Q

Two major lineages:

A

Myeloid precursor and lymphoid precursor

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2
Q

Type of the immune system responsible for the maturation of antigen-reactive cells.

A

Primary response

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3
Q

Type of immune system responsible for antigen contact and response

A

Secondary response

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4
Q

Two main type of tissue that disposes worn-out bloodness

A

Red pulp

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5
Q

Two main type of tissue that contains the lymphoid tissue

A

White pulp

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6
Q

Large white cells that can engulf and digest marauding microorganism and other antigenic particles. Some have the ability to present antigen to lymphocytes

A

Phagocytes

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7
Q

Important phagocytes

A

Monocyte and macrophage

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8
Q

Other antigen-presenting cells;

A

B cells, macrophage, type 1 & 2 dendritic cells

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9
Q

Irregularly shoed wbc. Have long threadlike tentacles that enmesh lymphocytes and antigens. Can be found in spleen.

A

Dendritic cells

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10
Q

These are dendritic cells that travel in the skin, picking up antigen and transporting it to lymph nodes. Found in pancreas

A

Langerhans cells

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11
Q

They play a key role in acute inflammatory response

A

Neutrophils

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12
Q

It is a noncirculating counterpart of the basophil. Located in the lungs, skin, tongue, and linings of the nose and intestinal tract. Responsible for the symptoms of allergy.

A

Mast cell

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13
Q

F: SRBC receptor, t cell adhesion/ activation

A

CD2

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14
Q

Signal transduction

A

CD3

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15
Q

Co-recognition of MHC class 2 with TCR, primary receptor of HIV retrovirus

A

CD4

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16
Q

Involved in signaling through TCR and BCR

A

CD5

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17
Q

Involved in T cell proliferation, cell adhesion

A

CD6

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18
Q

Co-recognition of MHC class 1 with TCR

A

CD8

19
Q

Regulation of B cell growth and proliferation

A

CD10

20
Q

Granulocytes neutrophil only

A

CD16b

21
Q

Receptor for LPS and LBS

A

CD14

22
Q

Mediates signal transduction on NK cells

A

CD16a

23
Q

Signals transduction regulating B cell responsiveness

A

CD19

24
Q

Involved in B cell proliferation/activation, part of the signal transduction complex

A

CD21

25
Q

Regulates IgE synthesis, mediates cytotoxicity by macrophage and eosinophil

A

CD23

26
Q

Involved in T cell and C cell activation/proliferation

A

CD27

27
Q

T cell co-stimulatory signal

A

CD28

28
Q

Regulatory B cell

A

CD32

29
Q

Negative regulatory role in myeloid hematopoiesis. Important in distinguishing myeloid from lymphoid leukemia.

A

CD33

30
Q

Stem cell marker, adhesion

A

CD34

31
Q

Maintains adherence of C4b/C3d- coated particles for phagocytosis

A

CD35

32
Q

Involved in B cell differentiation, promotes macrophage cytokine production.

A

CD40

33
Q

Central role of platelet activation/proliferation

A

CD41

34
Q

Required for T and B cell antigen receptor mediated activation/tyrosine phosphatase

A

CD45

35
Q

Mediated homophilic adhesion

A

CD56

36
Q

Phagocytosis, involved in antigen capture, antibody-dependent cellular cytotoxity

A

CD64

37
Q

Inhibits phagocytosis

A

CD65s

38
Q

Involved in B cell activation/proliferation

A

CD72

39
Q

Transmit signals into cytoplasm on antigen binding to surface Igs

A

CD79

40
Q

Involved in extravasation of leukocyte

A

CD87

41
Q

Induces phagocytosis, degranulation, respiratory burst, killing of microorganism

A

CD89

42
Q

Mediator of phagocytosis

A

CD91

43
Q

Regulator for megakaryocyte and platelet formation, prevention of apoptosis

A

CD110

44
Q

Growth factor receptor

A

CD117

45
Q

Signaling for IL-2,4,7,9,15

A

CD132