Cells and Neurotransmitters Flashcards
What are the 2 types of cells within the nervous system
Glial cells and neurons
What are neurons
Electrically conductive, take infor from brain and move it around
What are glia
protect neurons by giving structure
What are the 3 mechanisms that help molectular transport?
Passive diffusion (fat soluble molecules)
Facilitated diffusion through channels
Active transport
What is resting membrane potential
The inside of cell is negative, outside is more positive
More sodium moves out and less potassium moves in, making outside more positive and inside more negative
Action potential steps
If the charge exceeds -55mV, neuron fires action potential
- Na+ channels open and enter cell, making cell more positive (Marks rising phase)
- K+ channels open and leave cell
- Na+ channels close, cell peaks at positive voltage (Marks repolarization phase)
4.K+ channels close, cell returns to initial charge (Marks hyperpolarization phase)
What do action potentials do?
Cause nearby cells to send action potentials, traveling quickly on myelinated axons
Initial charge caused by stimulus in sensory cell or by inputs of other neurons
Terminal button at end of axon, allowing neurotransmitters to be released into synapse
What is a synapse?
Small active gap between neurons
Presynaptic (send), postsynaptic (recieve)
Postsynaptic neurons have receptors that fit with specific neurons
What is the general role of neurotransmitters
Binding to corresponding receptors and push the charge of postsynaptic cells up or down
How are NTs removed
diffuse away, broken down by enzymes, reuptaken by presynaptic neurons
3 Types of NTs
Excitatory: making neuron more likely to fire AP
Inhibitory: making neuron less likely to fire AP
Modulatory: trigger other changes
Agonist?
Turns on receptors and activates it effects
Antagonist?
Block receptors from being turned on
Reuptake inhibitors
blocks NT clean up, allowing NTs to have more chance to bind to receptors
Oligodendroglia
Wraps aroud neurons in CNS, and forms myelin sheaths per cell
Schwann cells
type of glia
wraps around axons in PNS, forming 1 myelin sheath per cell
Microglia
respond to injury/disease, eating debris and triggering immune response