Cell Turnover Flashcards

1
Q

Growth

A

Process of increase in size resulting from the synthesis of specific tissue components

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2
Q

Growth

A

Process of increase in size resulting from the synthesis of specific tissue components

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3
Q

Types of growths and their characteristics

A

Multiplicative-increase in cell number as result of mitosis
Auxetic-increase in cell size
Accretionary-increase in intercellular rissue components
Combined

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4
Q

Differentiation

A

Process whereby a cell develops an overt specialized function or morphology that is distinguished from its parent cell

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5
Q

Morphogenesis

A

Highly complex development of structural shape and form of organs, limbs, facial features

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6
Q

Cell poriferation

A

Fundamental to :
Development
Maintainance of steady state tissue homeostasis
Replacement of dead or damaged cells

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7
Q

Cell phases

A
G1-presynthetic phase
Restriction point
G1/S Checkpoint
S-DNA synthesis
G2-pre mitotic growth
G2/M checkpoint
M_mitosis
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8
Q

CDKN1 inhibitiors

A

p21
p27
p57

Broadly inhibit CDKs

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9
Q

CDKN2 Inhibitiors

A

p15 b
p17 a
p18 c
p19 d

Selectively effects on 4 and 6

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10
Q

Two essential properties of stem

A

Self renewal

Asymmetric division

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11
Q

Stem cell locations

A
Bone marrow
Bulge of hair follicle
Limbuds of the eye
Canals of herrin in the liver
Supraventricular zone of the brain
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