Cell surface proteins

Question 1

CD1

Answer 1

MHC molecule that presents lipid molecules

Question 2

CD2

Answer 2

Found on thymocytes, T cells, and some natural killer cells that acts as a ligand for CD58 and CD59 and is involved in signal transduction and cell adhesion

Question 3

CD3

Answer 3

The signalling component of the T cell receptor (TCR) complex

Question 4

CD4

Answer 4

Found on helper T cells.
Co-receptor for MHC class II
Used by HIV to enter T cells

Question 5

CD5

Answer 5

Found in the majority of mantle cell lymphomas

Question 6

CD8

Answer 6

Found on cytotoxic T cells.
Co-receptor for MHC class I
Found on a subset of myeloid dendritic cells

Question 7

CD14

Answer 7

Cell surface marker for macrophages

Question 8

CD15

Answer 8

Expressed on Reed-Sternberg cells (along with CD30)

Question 9

CD16

Answer 9

Bind to the Fc portion of IgG antibodies

Question 10

CD21

Answer 10

Receptor for Epstein-Barr virus

Question 11

CD28

Answer 11

Interacts with B7 on antigen presenting cell as costimulation signal

Question 12

CD45

Answer 12

Protein tyrosine phosphatase present on all leucocytes

Question 13

CD56

Answer 13

Unique marker for natural killer cells

Question 14

CD95

Answer 14

Acts as the FAS receptor, involved in apoptosis