cell proliferation Flashcards
Define neoplasia
Formation of new abnormal growth tissue
Define tumour
Swelling of part of body caused by abnormal growth of tissue, can be malignant or benign
Define mutagenesis
Production of genetic mutations
Define oncogenesis
Development of tumour(s)
Define angiogenesis
Development of new blood vessels
Define cancer
Term that embraces vast diversity of diseases
Cancer cells divide continuously
Behave differently to normal cells
Have altered metabolism
What does loss of cell cycle control in neoplasia lead to?
Uncontrolled growth
Proliferation of cells
Accumulation of mutations
Development of resistance to apoptosis
What is necrosis?
Lethal cell injury or accidental cell death in living organism
Caused by injury, infection, cancer, infarction, toxins or inflammation
What is apoptosis?
Programmed cell death
Tightly regulated
Involved in embryo development, tissue turnover & pathological stages
