Cell Organelles And Cytoplasm, Membrane Transport Flashcards
Cytology
Study of cellular structure and function
Robert Hooke’s Ideas
Cells are building blocks
All cells come from division of preexisting cells
Cells are smallest unit that perform all vital physiology functions
Each cell maintains homeostasis at cellular level
Plasma membrane
Lipids and cholesterol
Protein
Carbs
Cytoplasm
Cytosol and organelles
Organelles: Cytoskeleton
Microfilament (microvilli), intermediate filament, microtubules
Organelles list
Centrosome, centriole, ribosome, proteasome, microvilli, flagella, cilia, ER, golgi apparatus, lysosomes, peroxisomes, mitochondria
Membrane transport
Diffusion, osmosis/osmolarity, tonicity
Functions of plasma membrane
Physical/isolation barrier, regulation of exchange, eliminates waste and releases cellular product, sensitivity, structural
Phospholipid bilayer
Hydrophobic tails, hydrophilic heads, barrier to ions and water
Membrane Protein: anchoring proteins
Attach to inside or outside structures
Membrane Proteins: Recognition Proteins
Label cells as normal or abnormal
Membrane Proteins: Enzymes
Catalyze reactions
Membrane Proteins: Receptor Proteins
Bind and respond to ligands (ions, hormones)
Membrane Proteins: Carrier Proteins
Transport specific solutes through membrane
Membrane Proteins: Channels
Regulate water flow and solutes through membrane
Cytoplasm: cytosol (intracellular fluid)
Dissolved materials (nutrients, ions, protein, waste prod), high potassium/low sodium, high protein, high carb/low amino acids + fat
Cytoskeleton: structural proteins
For shape and strength
Microfilaments, intermediate filaments, microtubules
Microvilli
Increase surface area for absorption, attach to cytoskeleton
Intermediate filaments
Mid-sized between microfilaments and thick filaments
Intermediate filaments purpose
Durable (collagen), strengthen cell and maintain shape, stabilize organelles, stabilize cell position
Cilia
Small hair-like extensions, move fluids
Ribosomes
Build polypeptides into protein synthesis
Ribosomes: two types are…
Free ribosomes, fixed ribosomes
Free ribosomes
Manufacture proteins in cell, in cytoplasm
Fixed ribosomes
Attached to ER, manufacture proteins for secretion
Endoplasmic Reticulum (ER) name breakdown
Endo = within
Plasm = cytoplasm
Reticulum = network
Cisternae
Storage containers within membranes in ER
ER functions
- Synthesis of protein, carbs, lipids
- Storage of synthesized molecules and materials
- Transport of materials
- Deoxtification
Smooth endoplasmic reticulum (SER)
No ribosomes; synthesizes lipids and carbs
SER: synthesizes lipids and carbs such as..
Phospholipids and cholesterol
Steroid hormones
Glycerides
Glycogen
RER functions
Active in protein and glycoprotein synthesis
Folds polypeptide protein structures
Encloses products in transport vesicles
Golgi Apparatus
Vesicles entering and leaving; hormones and enzymes released through exocytosis
Lysosomes
Digestive enzymes, recycle damaged proteins, autolysis
Autolysis
Break up of lysosomes, self destruct to cell decompose
Peroxisomes
Enzyme-containing vesicles, Break down fatty acids, organic compilation
Mitochondria
Smooth outer membrane, inner membrane w folds (cristae)
Mitochondria produces
ATP
Nucleus
Largest organelle, control cemter
Diffusion
Movement down a concentration gradient
Osmosis
Movement of water from low solute to high solute
Hydrostatic pressure
Force needed to equalize water lvld after physical pushing of water
Osmotic pressure is equal to
Hydrostatic press.
Isotonic
Does not cause osmotic flow of water
Hypotonic
Less solute, loses water
Hypertonic
More solute, gains water
Cells in hypertonic solution
Crenate, water moves out
Cells in hypotonic solution
Ruptures (hemolysis)
Selectively permeable
Restricts movement; nutrients get in and wastes go out
Simple diffusion
Lipid-soluble compounds (alcohols, fatty acids, steroids)
Dissolved gases (oxygen and carbon dioxide)
Channel-mediated diffusion
Water-soluble compounds and ions
Facilitated Diffusion
Molecule binds to receptor site on carrier protein; protein changes shape, molecules pass through
Active transport
Pumps that use ATP; move against concentration gradient
Endocytosis
Active transport using ATP
Receptor-mediated, pinocytosis, phagocytosis
Vesicular Transport
Bulk transport, materials move in or out of cells
Endocytosis: pinocytodis
Endosomes drink extracellular fluid
Phagcytosis
Engulf large objects in phagosomes
Receptor-mediated endocytosis
Receptors bind target molecules (ligands); coated vesicle (endosome) carries ligands and receptors into cell
Exocytosis
Granules/droplets released from cell; opposite of endocytosis