cell mediated response

Question 1

what are lymphocytes

Answer 1

-Lymphocytes are white blood cell involved in the specific immune response

Question 2

Where do t-lymphocytes mature

Answer 2

-T-lymphocytes mature in the Thymus but made in the bone marrow

Question 3

What is a APC

Answer 3

—Antigen presenting cell that presents a non-self antigen on its surface :
•infected body cells
•a phagocyte which has engulfed and destroyed a pathogen
•cells from transplanted organs
•cancer cells

Question 4

What are the steps in cell meditated response

Answer 4

1. Once a pathogen has been engulfed and destroyed by a phagocyte, the antigens are positioned on the cell surface.This is now called an (APC)
2. Helper T cells have receptors on their surface which can attach to the antigens on APC.
3. Once attached this activates the helper T cells to divide by mitosis to replicate and make large of clones
4. Cloned helper T cells differentiate into different cells:
   •Some remain as helper T cells and activate B lymphocytes
   •Some stimulate phagocyte to perform more phagocytosis
   •Some become memory cells for that shaped antigen
   •Some become cytotoxic T cells (killer T cells)

Question 5

What are cytotoxic t cells

Answer 5

Cytotoxic T cells destroy abnormal or infected cells.
They release a protein, perforin, which embeds in the cell surface membrane and makes a pore (a hole) so that any substances can enter or leave the cell.
This causes the cell death.