active transport , cotransport Flashcards
what is active transport
-The movement of molecules and ions through a cell membrane against the concentration gradient using energy from respiration.
-Requires ATP and carrier proteins
What is active transport used for
-Uptake of glucose and amino acids in the small intestine
-Absorption of mineral ions by plant roots
-Excretion of hydrogen ions and urea by kidneys
-Exchange of sodium and potassium ions in neurons and muscle cells.
when is bulk transport used
-When extremely large substances need to be moved across a cell membrane
What is endocytosis
-Endocytosis is the bulk transport of material INTO the cell, and can be split into three processes: phagocytosis, pinocytosis and receptor-mediated endocytosis.
What is exocytosis
-Exocytosis is the bulk transport of material OUT of the cell – essentially the reverse of endocytosis.
Details of active transport
- Transport is through carrier proteins spanning the cell membrane.
- Molecule binds to the receptor complementary in shape of protein.
- ATP binds to the carrier protein from inside the cell and it is hydrolysed into ADP + Pi
- This causes the carrier proteins to change shape and release the molecule to other side
- The phosphate ion is then released and the protein returns to its original shape.
What is co-transport
-Co-transporters use concentration gradient of one molecule (Na+) to move another molecule against its concentration gradient (glucose)
What are the 2 section of small intestine
-duodenum = most digestion
-ileum = absorption of nutrients & water
Factors which affect the rate if absorption
-Folded membrane/microvilli s o large surface area (for absorption)
-Large number of carrier proteins so fast rate (of absorption)
-Large number of mitochondria so make more ATP by respiration
Transport of sodium ions and glucose
-Na+ ions leave epithelial cell and enter blood by active transport via carrier proteins using (the hydrolysed ) ATP
-So Na+ concentration in cell is lower than in lumen which maintains a gradient
-Sodium/Na ions enter by facilitated diffusion;
-Glucose absorbed with Na ions against their concentration gradient