Cell division, cell diversity & cell differentiation 2.6 Flashcards
What is a chromatid?
Replicates of chromosomes
What are the phases of the cell cycle?
- interphase
- mitosis
- cytokinesis
What is mitosis?
Type of nuclear division that maintains the chromosome number
What is the importance of mitosis?
- asexual reproduction
- growth
- tissue repair
What are the stages of mitosis?
- prophase
- metaphase
- anaphase
- telophase
- cytokinesis
What happens during prophase in mitosis?
- DNA supercoils and condenses becoming visible
- nuclear envelope breaks down
- spindle fibres form
What happens during metaphase in mitosis?
- Chromatids attach to the spindle fibres by their centromeres
- line up in the equator region
What happens during anaphase in mitosis?
- centromere of each pair of chromatids splits
- spindle fibres contract
- sister chromatids are pulled to opposite directions
What happens during telophase in mitosis?
- chromosomes reach the poles
- nuclear envelope forms
- chromosomes uncoil and decondense
What happens during cytokinesis in mitosis?
Plasma membrane folds inwards and rips the cytoplasm
What is cytokinesis?
Division of the cytoplasm of a cell following mitosis
What are the phases of interphase?
- G1
- s
- G2
What are the two main checkpoints during the cell cycle?
- G1 checkpoint
- G2 checkpoint
- spindle assembly checkpoint
What are the purpose of the checkpoints?
- prevent uncontrolled division
- detect and repair damage to DNA
- ensure the cell cycle is not reversed
- ensure DNA is only duplicated once
What happens during the M phase of the cell cycle?
- cell stops growing
- cell undergoes nuclear division
What happens during the G0 phase of the cell cycle?
- It is a resting phase
- cells may undergo apoptosis, differentiation or senescence
What happens during the G1 phase of the cell cycle?
- cell growth
- organelles duplicate
- trancription to create RNA
- protein synthesis
What happens during the S phase of the cell cycle?
- cell now has to commit to completing the cycle
- DNA replicates
What happens during the G2 phase of the cell cycle?
- Cells grows
- proteins involved with mitosis are stimulated
What is meiosis?
Type of nuclear division that results in the formation of cells containing half the number of chromosomes of the parent cell
How does meiosis produce genetic variation?
- crossover
- independent assortment of homologous pairs of chromosomes