Cell division and Cellular Organization Flashcards

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1
Q

What is the stages of the cell cycle

A

G1, G1 checkpoint, S, G2, G2 checkpoint

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2
Q

What happens during G1

A

Cell grows and new organelles and proteins are made

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3
Q

What happens during G1 checkpoint

A

The cell check that the chemicals needed for replication are present and for any damage to the DNA before enters S phase

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4
Q

What happens during S phase

A

Cell replicates its DNA ready to divide by mitosis

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5
Q

What happens during G2

A

Cell keeps growing and proteins needed for cell division are made

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6
Q

What happens during G2 checkpoint

A

The cell checks whether all the DNA has been replicated without any damage. If it has, the cell can enter mitosis.

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7
Q

What happens during M phase

A

Mitosis and cytokinesis

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8
Q

What are the stages of mitosis

A

Interphase, prophase, metaphase, anaphase, telophase, cytokinesis

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9
Q

What happens during interphase

A

The cell carries out normal functions but also prepares to divide. The DNA is unraveled and replicated to double its genetic content. Organelles are replicated and ATP is increased

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10
Q

What happens during prophase

A

The chromosones condense getting shorter and fatter. Centrioles (bundles of protein) start moving to opposite ends of the cell forming a protein network - spindle. The nuclear envelope breaks down and chromosomes lie free in the cytoplasm

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11
Q

What happens during metaphase

A

The chromosomes line up along the middle of the cell and become attached to the spindle by their centromere. The cell check all the chromosomes are attached to the spindle before mitosis can continue

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12
Q

What happens during anaphase

A

The centromeres divide separating each pair of sister chromatids. The spindles contract, pulling chromatids to opposite ends of the cell, centromere first

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13
Q

What happens during telophase

A

The chromatids reach the opposite poles on the spindle. They uncoil becoming long and thin now called chromosomes. A nuclear envelope forms around each group of chromosomes so now two nuclei

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14
Q

What happens during cytokinesis

A

The cytoplasm divides. In animals a cleavage furrow forms now two genetically identical daughter cells are formed.

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15
Q

How do you observe the cell cycle

A

By staining the chromosomes so you can see them under a microscope and therefore be able to watch what happens during mitosis

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16
Q

What does meiosis produce and where

A

The reproductive organs producing gametes

17
Q

What type of division is meiosis

A

Reduction division. This is where the cells that are formed have half the number of chromosomes (diploid)

17
Q

What happens in meiosis I

A

Prophase I = Chromosomes condense, getting shorter and fatter then arrange themselves into homologous pairs. Centrioles move them to opposite ends forming spindle fibres. Nuclear envelope breaks down

Metaphase I = The homologous pairs line up across the centre of the cell and attach to the spindle fibres by their centromeres

Anaphase I = The spindles contract separating the pairs one chromosome to each end of the cell

Telophase I = A nuclear envelope forms around each group

Cytokinesis = two haploid daughter cells produced

18
Q

What are homologous pairs

A

Pairs of chromosomes one from mum and one from dad

19
Q

What happens during meiosis II

A

Daughter cells undergo the stages again. In anaphase II the pairs of sister chromatids are separated and each new daughter cell inherits one chromatid from each chromosome

20
Q

What happens to homologous pairs during meiosis I

A

Come together and pair up, the chromatids twist around each other and bits of chromatids swap over. The chromatids still contains the same genes but now a different combination of alleles

21
Q

What are the two main events during meiosis that lead to genetic variation

A

Crossing over of chromatids - daughter cells formed contain chromatids with different alleles

Independent assortment of chromosomes

22
Q

What are stem cells

A

Unspecialized cells that can develop into different types. They divide to become new cells which specialize for a certain job called differentiation.

22
Q

Why does the independent assortment of chromones lead to genetic variation

A

1) Each homologous pair is made from one chromosome that is maternal and one paternal chromosome

2) When pairs line up in metaphase I and separated in anaphase I it is completely random which chromosome from each pair ends up in which daughter cell

3) The four daughter cells have different combinations of maternal and paternal

4) This is an independent assortment of chromosomes

5) The shuffling leads to genetic variation

22
Q

What do cells in bone marrow differentiate to

A

Blood cells - erythrocytes and neutrophils

23
Q

What do cells in meristems differentiate into

A

Xylem and phloem sieve tubes

24
Q

How does research show stem cells might cure Parkinson’s and Alzheimer’s

A
  • Regrow healthy nerve cells in the brain for Alzheimer’s
  • Parkinson’s suffer from tremors that they cannot control. Transplanted stem cells may regenerate the dopamine-producing cells