Cell Division Flashcards
Name the 3 stages in the cell cycle
Interphase, Mitosis and Cytokinesis
What 3 sub stages does interphase consist of
G1
S
G2
What happens during G1
Duplicating organelles
Growing in size
Making proteins needed for S phase
What is/happens in S phase
Synthesis, DNA synthesis happens (DNA is replicated)
Most important sequences of DNA replicated first (Housekeeping genes)
What specifically happens at the end of S phase
All of chromosomes will be replicated
How can cells exit the cell cycle
Enter G0 phase by exiting cell cycle at start of G1
What cells do after entering the G0 phase
Differentiate, die or senescence
What happens during G2
Cell keeps growing an proteins needed for cell division are made
Name 4 uses of mitosis
Wound repair
Growth
Tissue repair
Asexual reproduction
What is the point of Cell Cycle checkpoints
Damage to DNA can occur during DNA replication in interphase, e.g wrong base replicated (mutation)
Why is DNA replication in S phase kept short
Exposed bases are more susceptible to mutation
Name the two things that checkpoints check
Damaged/mutated DNA is detected and repaired
DNA is only replicated once in each cycle (rate of cell division)
What does the G1 checkpoint look for and where is it
End of G1
Checks chemicals needed for replication and any damaged DNA, ready for S phase
What does the G2 checkpoint look for and where is it
End of G2
Checks whether all DNA has been replicated without damage, ready for mitosis
What does the metaphase checkpoint look for and where is it
During mitosis (in metaphase) Cell checks all chromosomes are attached to spindle before mitosis continues