Cell Cycle Cell Division Flashcards
What is cell cycle?
Events in which cell duplicates its genome and other contents and eventually divides into daughter cells.
Duration of cell cycle in
1️⃣Bacteria
2️⃣Yeast
3️⃣Human cells
Bacteria = 20min
Yeast =90min
Human cell = 24hrs
Duration of interphase is
Almost 95% of the total duration of cell cycle.
Which is the intense phase related to growth
Interphase.
Events that occur in G1 phase are:
Most Organelles duplicate.
Cell is metabolically active and grows continuously.
Events that occur in S phase are
DNA 🧬 replication .
Histone protein synthesis
Centriole replication
Sub-units for kinetochore are synthesized.
Duration of G1 phase in humans is ______, S phase is _____ and G2 phase is
G1 phase= 10hrs
S phase= 9hrs
G2 phase= 4hrs
Events that occur in G2 phase are
Proteins and RNA synthesis continues.
Tubulin protein is synthesized.
Final preparation for M-phase occurs.
Events in Go- phase are
Cell is metabolically active but no longer proliferates.
Cell decides to enter Go phase in M-phase.
Name the 4 stages of karyokinesis?
Prophase Metaphase Anaphase Telophase (Prof. Mehmood ah. Tak)
Events of early prophase are
Chromatin condensation occurs
Centriole pair start separating
Chromosome ends are not clearly visible.[spireme stage]
Viscosity increases.
Events in mid prophase
Centriole pair moves farther apart.
Chromatin condensation occurs.
# Aster formation starts.
Events in late prophase are
Spindle formation is ‘almost’ completed.
Aster formation ‘almost’ complete.
Chromosomes are fully condensed.
Events that occur in pro-metaphase
Aka 5th phase
Aster formation completed.
Spindle formation completed.
Mitotic apparatus (spindle & aster) is formed.
Events in metaphase are
▪️Congression metakinesis ( process of bringing of chromosomes from different locations towards equator).
▪️Chromosomes are fully condensed.
▪️Only metaphasic plate or equatorial plate is formed.
Chromosomes are attached with spindle fibres with the help of ___________
Kinetochores.
Events of anaphase are
Centromeric division occurs = Separation of sister chromatids = now called Chromosomes
DOUBLING OF CHROMOSOME NUMBER.
Best stage to study the shape of chromosomes are
Anaphase
Best stage for studying chromosome morphology is
Metaphase.
Match the following: 1️⃣Metacentric I 2️⃣Sub-metacentric. J 3️⃣Acrocentric L 4️⃣Telocentric V
Metacentric = V shaped
Sub metacentric = L shaped
Acrocentric = J shaped
Telocentric = I shaped
Rate of anaphasic movt. Of chromosomes is
0.2 - 5 μm/min