Cell Cycle and Cell Division Flashcards

1
Q

What is a haploid cell in humans?

A

n
23 chromosomes
Gametes

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2
Q

What is a diploid cell in humans?

A

2n
23 Chromosome pairs
Somatic (body) cell

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3
Q

What are the stages in the cell cycle?

A

Interphase- a period of synthesis and growth
Mitosis- Formation of two genetically identical nuclei
Cytokineses- Division of cytoplasm to form two daughter cells

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4
Q

What are the stages in interphase?

A

G1 phase - growth and normal metabolic roles
S phase - DNA replication
G2 phase - growth and preparation for mitosis by organelle replication

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5
Q

What is the order of the stages in mitosis?

A

Prophase
Metaphase
Anaphase
Telophase

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6
Q

What’s the structure of a chromosome in prophase?

A

Two chromosomes joined at centromere with sister chromatids opposite each other

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7
Q

What occurs in interphase?

A
  • high metabolic activity
  • requires ATP
  • cell increases in size
  • DNA and organelles replicate
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8
Q

What occurs in prophase?

A
  • chromosomes condense
  • centrioles divide and move to opposite poles
  • nuclear envelope disappears
  • spindle forms
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9
Q

What occurs in metaphase?

A
  • chromosomes line up on equator

- spindle fibres attach to centromere

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10
Q

What occurs in anaphase?

A
  • spindle fibres shorten
  • centromeres divide
  • sister chromatids separate
  • each is pulled to opposite side of the cell
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11
Q

What occurs in telophase?

A
  • chromosomes uncoil and lengthen
  • spindle breaks down
  • nuclear envelope reforms
  • nuclear division is complete
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12
Q

How does the spindle differ in plant and animal cells?

A

In animal cells the spindle degenerates at telophase

In plant cells the spindle remains throughout new cell wall formation

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13
Q

Where does mitosis occur in plant and animal cells?

A

Animal cells:
Epithelia, bone marrow, gut lining

Plant cells:
Meristems

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14
Q

How does cytokineses occur in animal cells?

A

The construction of the parent cell creates a cleavage furrow dividing the cell from the outside inwards

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15
Q

How does cytokineses occur in plant cells?

A

Droplets of cell wall material form a cell plate across the equator from the inside outwards to extend and join to create a new cell wall

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16
Q

Where are centrioles found?

A

In animal cells but not plants

17
Q

Why does mitosis give genetic stability?

A

It maintains the chromosome number by producing genetically identical daughter cells

18
Q

How is mitosis used for growth?

A

It increases cell number and can also be used to repair tissue and replace dead cells

19
Q

What is asexual reproduction?

A

Produces genetically identical offspring

Takes place in unicellular organisms (yeast, bacteria) and some plants and tubers (strawberries)

20
Q

How can the cell cycle be affected?

A

By damage to the genes which control it

Through radiation, chemicals and viruses which may stop division or cause uncontrollable division

21
Q

What happens when cells divide uncontrollably?

A

Tumors such as cancers are formed

22
Q

How are tumours controlled?

A

Tumour suppressing genes

23
Q

What are proto-oncogenes and what do they become?

A

They are genes that have the potential to cause cancer and when they mutate they become oncogenes