cell cycle Flashcards
what are the stages in a cell cycle?
mphase- pmat
interphase- 1.G1-G0 2.S phase 3.G2 phase
what are the two checkpoints?
G1/S phase
G2/M phase
what is the purpose of the checkpoints?
1.to prevent uncontrolled cell division
2. to detect repair and damage
3.to ensure the cell cycle cannot be reversed
4.DNA is duplicated only once during the cell cycle
describe the M phase
this is the stage in which the cell goes through mitosis
cell growth stops
nuclear division (pro,meta,ana,telo phase)
cytokinesis
what happens in the check point of the M phase?
triggers condensation of chromatin
meta phase checkpoint ensures that the cell is ready to complete mitosis
describe the G1 phase
cells grow and increase in size
transcription of RNA
protein synthesis and synthesis of some DNA enzymes
organelles duplicate
the p35(tumor suppressing) gene helps control this hase
what’s the purpose of the G1 Checkpoint
its a control mechanism which ensure the cell is ready to enter the S phase and begin DNA synthesis.
describe the G0 phase
its a phase within the G1 where cells undergo
differentiation
apoptosis(programmed cell death)
enter senescence (where they can no longer divide)
describe the S phase
it is committed to completing the cell cycle
DNA replicates
each one consists of a pair of sister chromatid after duplication
This phase is rapid to prevent genetic mutation from happening.
what are housekeeping genes and why are they replicated last?
Because they contain the genes that are active in every cell