cell cycle Flashcards

1
Q

what are the stages in a cell cycle?

A

mphase- pmat
interphase- 1.G1-G0 2.S phase 3.G2 phase

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2
Q

what are the two checkpoints?

A

G1/S phase
G2/M phase

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3
Q

what is the purpose of the checkpoints?

A

1.to prevent uncontrolled cell division
2. to detect repair and damage
3.to ensure the cell cycle cannot be reversed
4.DNA is duplicated only once during the cell cycle

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4
Q

describe the M phase

A

this is the stage in which the cell goes through mitosis
cell growth stops
nuclear division (pro,meta,ana,telo phase)
cytokinesis

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5
Q

what happens in the check point of the M phase?

A

triggers condensation of chromatin
meta phase checkpoint ensures that the cell is ready to complete mitosis

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6
Q

describe the G1 phase

A

cells grow and increase in size
transcription of RNA
protein synthesis and synthesis of some DNA enzymes
organelles duplicate
the p35(tumor suppressing) gene helps control this hase

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7
Q

what’s the purpose of the G1 Checkpoint

A

its a control mechanism which ensure the cell is ready to enter the S phase and begin DNA synthesis.

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8
Q

describe the G0 phase

A

its a phase within the G1 where cells undergo
differentiation
apoptosis(programmed cell death)
enter senescence (where they can no longer divide)

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9
Q

describe the S phase

A

it is committed to completing the cell cycle
DNA replicates
each one consists of a pair of sister chromatid after duplication
This phase is rapid to prevent genetic mutation from happening.

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10
Q

what are housekeeping genes and why are they replicated last?

A

Because they contain the genes that are active in every cell

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