Cell Bio final-Immune Flashcards

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0
Q

Humoral immunity and Cell-Mediated immunity are types of?

A

Acquired immunity

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1
Q

Innate immunity lacks the memory of an infection and these cells respond first to inflammation

A

Neutrophils

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2
Q

Plasma cells display memory in this type of immunity?

A

Humoral immunity

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3
Q

Macrophages, dendritic cells, and follicular dendritic cells are known as?

A

Accessory cells

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4
Q

Passive Immunity is inherited

T/F?

A

true, maternal immunity

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5
Q

Post disease gives rise to memory cells in case the antigen were to attack again. this describes?

A

Active Immunity

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6
Q

which are Primary Lymphoid organs?

A

thymus and bone marrow

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7
Q

Which are secondary lymphoid organs?

A

lymph nodes, tonsils, and spleen

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8
Q

what do Primary follicles lack?

A

germinal centers

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9
Q

Germinal centers and B cell Corona are characteristic of?

A

Secondary lymphoid follicles

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10
Q

This antibody is found in saliva, breast milk, GI tract, and respiratory tracts

A

Ig-A

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11
Q

In response to allergic reactions and in Parasitic worm infections like Paragonimus westermani (chinese lung fluke), this antibody is elevated

A

Ig-E

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12
Q

Whats the major immunoglobin found circulating in the blood and responsible for antibody reactivity?

A

Ig-G

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13
Q

Ig-M is the first antibody expressed on which cells?

A

B cells

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14
Q

B cells also express another antibody besides Ig-M. which one and it usually is associated with what maternal-fetal condition?

A

Ig-D. Rh incompatibility

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15
Q

Which part of an antibody binds to the antigen?

A

Fc region of Light chain

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16
Q

Which part of the antibody recognizes the antigen?

A

Fab region of the heavy chain

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17
Q

MHC class II proteins are involved in?

A

B cell maturation

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18
Q

CD8+ T cells are cytolytic in nature and recognize this on the surface of Macrophages

A

MHC I proteins

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19
Q

Which kind of T cells mature into helper T’s to recognize MHC II molecules?

A

CD4+

20
Q

MHC I molecules are found on the surface of all cells as a way of identifying their belonging to the body. it is NOT found on?

A

RBC’s and trophoblasts.

21
Q

What are the antigenic property antigens expressed from broken down foreign particles?

A

Epitopes

22
Q

Clonal expansion describes when T cells activate B cells to proliferate in response to antigen detection. T/F?

A

true

23
Q

according to the complement system, this pathway is activated by the antibody binding to the pathogen.

A

Classic

24
Q

What is the most important Opsonin?

A

C3b

25
Q

Opsonization is poking holes in the pathogen membrane by?

A

MAC- membrane attack complex…mac daddy!

26
Q

of the activation sequence, what initiates the complement cascade?

A

C1-s

27
Q

C1-q binds to which region of the Ig antibody?

A

Fc region

28
Q

4b2b combine to form?

A

C3 convertase

29
Q

Chemotaxis is a term to describe?

A

the release of chemokines to attract phagocytes to an area of infection/inflammation

30
Q

lymphocytes that pack a lymphoid organ refers to a?

A

Parenchyma

31
Q

Stroma consists of reticular fibers, undifferentiated cells, free and afixed macrophages? T/F?

A

hell yeah it’s true!!

32
Q

Are the Cortex and Center of a lymph follicle supplied by the same vascularization or different?

A

different!

33
Q

What is the entry and exit point for efferent and afferent lymhatics?

A

Lymph hilus

34
Q

The capsule of lymph follicles are composed of these fibers?

A

dense collagen fibers, elastic fibers, smooth muscle fibers

35
Q

Outer cortex of the lymph node contains?

A

follicles

36
Q

High endothelial venules are the entry point to the outer cortex. T/F?

A

FALSE!! it is for the INNER CORTEX

37
Q

Site of reentry into lymph stream

A

Medulla cortex

38
Q

Hassall’s corpuscles produce cytokines necessary for T cell maturation and are composed of single positive T cells. They are located in the?

A

Thymus Medulla

39
Q

Which cells enter the cortex from blood and proliferate in the subcapsular area?

A

Double negative T cells

40
Q

Double positive T cells move to this section of the thymus

A

outer cortex

41
Q

TCR receptors and either CD4 or CD8 receptors are expressed on these cells that eventually move to the inner cortex

A

Single positive T cells

42
Q

Splenic B cells with germinal centers are located?

A

White pulp of spleen

43
Q

Periarteriolar lymphoid sheath (PALs) are characteristic of?

A

splenic white pulp

44
Q

The site of erythrophagocytosis

A

Cords of Billroth in splenic red pulp

45
Q

These cells serve as antigen presenting phagocytic dendritic cells in the skin

A

Langerhan cells

46
Q

Melanin is derived from this amino acid

A

tyrosine

47
Q

sweat glands include merocrine and apocrine glands. T/F?

A

true.