Cell Bio final-Immune Flashcards

0
Q

Humoral immunity and Cell-Mediated immunity are types of?

A

Acquired immunity

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1
Q

Innate immunity lacks the memory of an infection and these cells respond first to inflammation

A

Neutrophils

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2
Q

Plasma cells display memory in this type of immunity?

A

Humoral immunity

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3
Q

Macrophages, dendritic cells, and follicular dendritic cells are known as?

A

Accessory cells

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4
Q

Passive Immunity is inherited

T/F?

A

true, maternal immunity

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5
Q

Post disease gives rise to memory cells in case the antigen were to attack again. this describes?

A

Active Immunity

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6
Q

which are Primary Lymphoid organs?

A

thymus and bone marrow

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7
Q

Which are secondary lymphoid organs?

A

lymph nodes, tonsils, and spleen

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8
Q

what do Primary follicles lack?

A

germinal centers

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9
Q

Germinal centers and B cell Corona are characteristic of?

A

Secondary lymphoid follicles

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10
Q

This antibody is found in saliva, breast milk, GI tract, and respiratory tracts

A

Ig-A

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11
Q

In response to allergic reactions and in Parasitic worm infections like Paragonimus westermani (chinese lung fluke), this antibody is elevated

A

Ig-E

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12
Q

Whats the major immunoglobin found circulating in the blood and responsible for antibody reactivity?

A

Ig-G

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13
Q

Ig-M is the first antibody expressed on which cells?

A

B cells

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14
Q

B cells also express another antibody besides Ig-M. which one and it usually is associated with what maternal-fetal condition?

A

Ig-D. Rh incompatibility

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15
Q

Which part of an antibody binds to the antigen?

A

Fc region of Light chain

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16
Q

Which part of the antibody recognizes the antigen?

A

Fab region of the heavy chain

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17
Q

MHC class II proteins are involved in?

A

B cell maturation

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18
Q

CD8+ T cells are cytolytic in nature and recognize this on the surface of Macrophages

A

MHC I proteins

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19
Q

Which kind of T cells mature into helper T’s to recognize MHC II molecules?

20
Q

MHC I molecules are found on the surface of all cells as a way of identifying their belonging to the body. it is NOT found on?

A

RBC’s and trophoblasts.

21
Q

What are the antigenic property antigens expressed from broken down foreign particles?

22
Q

Clonal expansion describes when T cells activate B cells to proliferate in response to antigen detection. T/F?

23
Q

according to the complement system, this pathway is activated by the antibody binding to the pathogen.

24
What is the most important Opsonin?
C3b
25
Opsonization is poking holes in the pathogen membrane by?
MAC- membrane attack complex...mac daddy!
26
of the activation sequence, what initiates the complement cascade?
C1-s
27
C1-q binds to which region of the Ig antibody?
Fc region
28
4b2b combine to form?
C3 convertase
29
Chemotaxis is a term to describe?
the release of chemokines to attract phagocytes to an area of infection/inflammation
30
lymphocytes that pack a lymphoid organ refers to a?
Parenchyma
31
Stroma consists of reticular fibers, undifferentiated cells, free and afixed macrophages? T/F?
hell yeah it's true!!
32
Are the Cortex and Center of a lymph follicle supplied by the same vascularization or different?
different!
33
What is the entry and exit point for efferent and afferent lymhatics?
Lymph hilus
34
The capsule of lymph follicles are composed of these fibers?
dense collagen fibers, elastic fibers, smooth muscle fibers
35
Outer cortex of the lymph node contains?
follicles
36
High endothelial venules are the entry point to the outer cortex. T/F?
FALSE!! it is for the INNER CORTEX
37
Site of reentry into lymph stream
Medulla cortex
38
Hassall's corpuscles produce cytokines necessary for T cell maturation and are composed of single positive T cells. They are located in the?
Thymus Medulla
39
Which cells enter the cortex from blood and proliferate in the subcapsular area?
Double negative T cells
40
Double positive T cells move to this section of the thymus
outer cortex
41
TCR receptors and either CD4 or CD8 receptors are expressed on these cells that eventually move to the inner cortex
Single positive T cells
42
Splenic B cells with germinal centers are located?
White pulp of spleen
43
Periarteriolar lymphoid sheath (PALs) are characteristic of?
splenic white pulp
44
The site of erythrophagocytosis
Cords of Billroth in splenic red pulp
45
These cells serve as antigen presenting phagocytic dendritic cells in the skin
Langerhan cells
46
Melanin is derived from this amino acid
tyrosine
47
sweat glands include merocrine and apocrine glands. T/F?
true.