Cefazolin Flashcards
Practical
Indications
Sepsis (where source is soft tissue / joint), and;
* Patient =>12 years
* Has 1 or more clinical features indicating antibiotics
* Time to hospital > 30 mins
* Compound fracture.
* Large contaminated wound.
* Following chest decompression.
* Following amputation.
* Cellulitis.
Contradindications
Known severe allergy to cephalosporins
Cautions
None
Actions
First generation antibiotic with activity against gram positive and gram negative bacteria.
Inhibits production of the bacteria cell wall.
Administration & Dose
IV :
* Dissolve 1g into 4ml NaCl.
* Dilute this to 10ml.
* Administer over 1 to 2 mins prefer running line.
Side Effects
None
Onset
30-60 mins
Duration
6-8 hours