CC Flashcards
Which if of the following refers to the chylomicrons?
A. Cathode
B. Anode
A. Cathode
It is the main storage lipid in humans (found in adipose tissue); constitutes 95% stored fat:
A. Cholesterol
B. Phospholipid
C. Fatty acids
D. Triglycerides
D. Triglycerides
Which of the following apoproteins is responsible for the receptor binding for IDL and the Chylomicron remnant produced in fat transport?
A. Apo A1
B. Apo C
C. Apo E
D. Apo B
C. Apo E
Which of the following apoproteins is inversely related to risk for coronary heart disease and is a surrogate marker for HDL?
A. Apo A-1
B. Apo B48
C. Apo B100
D. Apo E
A. Apo A1
Apo B48- chylomicrons
Apo B100- LDL, VLDV
Apo E- IDL
Which of the following would be most adversely affected by non fasting sample?
A. HDL
B. LDL
C. Cholesterol
D. Triglycerides
D. Triglycerides
Which type of lipids are steroids derived from?
A. Glyceride
B. Nonglyceride
C. Fatty Acid
D. Complex
B. Nonglyceride
Which of the following blood samples would serve the best to assay lipoproteins because this anticoagulant preserve lipoproteins?
A. EDTA plasma sample
B. Heparin plasma sample
C. Citrate plasma sample
D. Fluoride plasma sample
A. EDTA plasma sample
Which of the following lipoproteins is considered the smallest of all lipoproteins and is composed of 50% protein?
A HDL
B. Chylomicrons
C. Triglycerides
D. LDL
A. HDL
Which of the following is a rare autosomal recessive disorder characterized by the absence of VLDL, LDL and chylomicrons?
A. Bassen-Kornzweig syndrome
B. Tangier Disease
C. Anderson’s disease
D. Sitosterolemia
A. Bassen-Koenzweig Synderome
ApoB is absent
Which of the following is a rare autosomal recessive disorder characterized by the absence of HDL?
A. Bassen-Kornzweig syndrome
B. Tangier Disease
C. Anderson’s disease
D. Sitosterolemia
B. Tangier disease
Apo A is absent
Which of the following is a rare autosomal recessive disorder characterized by the absence of chylomicrons?
A. Bassen-Kornzweig syndrome
B. Tangier Disease
C. Anderson’s disease
D. Sitosterolemia
C. Andersons disease
Apo B48 is absent
At what serum glucose concentration would glucose begin to appear in the urine?
A. 50 mg/dl
B. 75 mg/dl
C. 100 mg/dl
D. 170 mg/dl
D. 170 mg/dl
Renal threshold: 160-180 mg/dl
Sodium renal threshold?
A. 50 mmol/L
B. 75 mmol/L
C. 100 mmol/L
D. 120 mmol/L
D. 120 mmol/L
Renal threshold: 110-130 mmol/L
The Dubowski method for glucose utilizes:
A. Arsenomolybdic acid
B. Orthotoluidine
C. G6PD
D. Mutarotase
B. Orthotoluidine
(Condensation reaction)
Which of the following is the most specific enzymatic method for glucose determination (employing G6PD as a second coupling step)?
A. Glucose oxidase
B. Glucose dehydrogenase
C. Hexokinase
D. Pyruvate Kinase
C. Hexokinase
What form of sugar in the liver is converted to glucose?
A. Starch
B. Cellulose
C. Glycogen
D. Amylopectin
C. Glycogen
Type 1 DM
I. Detectable C-peptide
II. Undetectable C-peptide
III. Most common in childhood/teens
IV. Most common in advancing age
A. I and III
B. III and IV
C. II and III
D. II and IV
C. II and III
There is low/no insulin for C-peptide to be detectable.
What is the Critical Value for hyperglycemia?
A. >200 mg/dl
B.>300mg/dl
C. >400mg/dl
D. > 500mg/dl
D.> 500mg/dl
A fasting blood sugar result of equal or greater then ____ is diagnostic for diabetes mellitus
A. 90mg/dl
B. 126mg/dl
C. 110mg/dl
B. 126mg/dl
90mg/dl- normal
110 mg/dl— impared
Which of the following methods is used as the primary reference method in the determination of HBA1c?
A. HPLC
B. Affinity chromatography
C. Ion-exchange chromatography
D. Immunoassay
A.HPLC
Preferred method(routine)- Affinity chromatography
Where does TCA(Kreb’s cycle) happens?
A. Mitochondria
B. Deoxyribonucleic acid
C. Ribonucleic acid
D. Golgi aparatus
A. Mitochondria
Abnormality of the hypoxanthine guanine phosphoribosyl transferase indicate problems with ___ metabolism
A. Purines
B. Pyrimidines
C. Myscle
D. Amino acid
A. Purines
Lesch-Nyhan Syndrome(Uric Acid)
End color of phosphotungstic acid (Caraway method) for uric acid?
A. Red
B. Orange
C. Blue
D. Yellow
C. Blue
Orange-Jaffe(Creatinine)
Yellow—Fearon’s(Urea)
Creatinine is formed in the
A. Liver
B. Muscles
C. Brain
D. Kidney
B. Muscles
Muscled metabolism- Creatinine
Protein metabolism- Urea
Purine metabolism- Uric Acid
Amino Acid Deamination- Ammonia
Dont stop
Padayun
In the direct Jaffe method for creatinine, a____ tauter of creatinine picrate is formed when creatinine is mixed with alkaline picrate reagent.
A. Yellow-green
B. Blue- green
C.Mauve lavender
D. Red-Orange
D. Red-Orange
Creatinine is expressed in
A. Umol/L
B. mL/s
C. mmol/L
D.mL/min
A. umol/L
Neurotoxic product of amino acid deamination:
A. Ammonia
B. Urea
C. Uric Acid
D. Creatinine
A. Ammonia
Albumin level in ascites:(Kwashiorkur)
A. Increase
B. Decrease
B. Decrease
Decrease: Albumin, protein, calorie
Most specific myocardial infraction:
A. Troponin I
B. Myoglobin
C. AST
D. CK-MB
A. Troponin I
Rise: 3-6hrs
Peak- 12-18hrs
Back to normal: 5-10days
True about CRP
I. Elevated in bacterial infection
II. It may be used as cardiac marker
III. It is an acute inflammatory marker
IV. It is a chronic inflammatory marker
A. I and III
B. I, II and III
C. All of these
B. I, II and III
Which test is used as an indicator of congestive heart failure
A. CRP
B. BNP
C. BTP
D. CTX
B. BNP
BTP- CSF leakage, perilymphatic fistulas
CTX- bone resobtion
Which of the following tests is a good marker of nutritional value?
A. Immunoglobulin M
B. Prealbumin
C. Ceruloplasmin
D. Lp(a)
B. Prealbumin
Ceruloplasmin- Wilson’s (copper)
Lp(a)- risk of congenital heart disease
Which of the following formula refers to globin?
A. Total protein+ Albumin
B. Total protein - Albumin
C. Total protein x Albumin
D. Total protein / Albumin
B. Total protein - albumin
What protein fraction migrates the farthest TOWARDS the anode?
A. Albumin
B. Alpha globulins
C. Beta globulins
D. Gamma globulins
A. Albumin
The last step in enzymatic measurement for cholesterol involves which reaction?
A. Trinder reaction
B. Caraway reaction
C. Diazo reaction
D. Fearow’s reaction
A. Trinder reaction
Caraway reaction- Uric Acid(Blue)
Diazo reaction- Bilirubin
Fearow’s reaction-Urea(Yellow)
Jaffe- Creatinine
Berthelot’s- ammonia
How is tolburamide administered in tolbutamide tolerance test?
A. Intramuscularly
B. Intravenously
C. Subcutaneously
D. Percutaneouslt
B. Intravenously
Conjugated bilirubin
1. Cannot appear in Urine
2. Can appear in Urine
3. Direct Bilirubin
4. Indirect Bilirubin
A. 1 3
B 1 4
C 2 3
D 2 4
In which of the following disease states would you see an elevation in total bilirubin and conjugated bilirubin only?
A. Biliary obstruction
B. Hemolytic anemia
C. Neonatal jaundice
D. Hepatitis
A. Biliary obstruction
Hemolytic anemia- ⬆️B1
Hepatitis-⬆️B1 ⬆️B2
Hepatocelluar damage may be best assessed by which of the following parameter?
A. Serum AST and ALT
B. Serum GGT, ALP
C. Bilirubin, GGT and ALP
D. Ammonia and Urea
A. Serum AST and ALT
Which test might be used to assess a person who is disoriented or confused?
A. Cholesterol
B. Ammonia
C. CRPs
D. Iron
B. Ammonia
Measurements of bilirubin in chemistry analyzers are based on
A. Nephelometry
B. Turbidimetry
C. Photometry
C. Photometry
Evelyn-Malloy-Methanol
Jendrassik-Grof- Caffiene
Which test might be ordered on a patient with abdominal pain to test for possible pancreatitis?
A. Amylase and lipase
B. Sodium and potassium
C. Cholesterol and triglyceride
D. C3 and C4
A. Amylase and lipase
Which of the following enzymes is the best indicator of pancreatic function?
A. AST
B. ALT
C. Amylase
D. Lipase
D. Lipase