CBC

Question 1

Common reasons for Leukocytosis

Answer 1

A.L.
Acute Infection (BFP, bacterial fungal or parasitic)
Leukemia (Chronic prob)

Question 2

Common reasons for Leukopenia

Answer 2

Infection (usually viral)
Bone marrow depression from meds, chemo, radiation, or disease
(aplastic anemia and certain stages and types of leukemia)

Question 3

Neutrophilia

Answer 3

infections, usually bacterial (fungal and parasitic also possible)
chronic myeloid leukemia

Question 4

Neutropenia

Answer 4

viral infections

aplastic anemia

Question 5

“band neutrophils” are?

Answer 5

band-shaped nucleus-means upregulated output of neutrophils so there is a current increase in immature cells.

Question 6

“segmented neutrophils”

Answer 6

segmented-shaped nucleus of neutrophils. mature neutrophils.

Question 7

Eosinophilia

Answer 7

Allergies and asthma
Parasitic disease
Several chronic diseases, including hematologic malignancies

Question 8

Basophila

Answer 8

Chronic inflammation
hematologic malignancies
Allergies

Question 9

Function of Monocytes

Answer 9

innate/acquired immunity.
scavenger function-clear blood of debris.
antiviral fxn in that they produce interferon.
3-10%

Question 10

Monocytosis

Answer 10

Recovery phase of an acute infection.
Some chronic infections!!!!!!!!!!!~particularly tuberculosis, syphilis, EBV.
Chronic autoimmune diseases

Question 11

Lymphocyte fxn

Answer 11

T and B cells, cannot be diff on cbc. T = adaptive immune response and memory. B = humoral immune response which involves the production of antibodies that will target specific antigens.

Question 12

Lymphocytosis

Answer 12

Viral infections.
TB and other mycobacterial inf.
Syphilis
Chronic lymphocytic leukemia

Question 13

Lymphocytopenia

Answer 13

Immunosuppression due to tx therapies like chemo or dz like AIDS or Hodgkin’s lymphoma.

Question 14

Common reasons for Reactive Lymphs:

Answer 14

“on MTV”
Mononucleosis
Tuberculosis
Viral Hepatitis

Question 15

Target cells are found in

Answer 15

thalassemias and post splenectomy

Question 16

Sickle cells are found in

Answer 16

sickle cell crisis

Question 17

Spherocytes are found in

Answer 17

autoimmune hemolytic anemia

Question 18

Schistocytes:

Answer 18

some hemolytic anemias with INTRAvascular destruction of RBCs(not autoimmune)

Question 19

Howell-Jolly Bodies inside RBCs are found in

Answer 19

“grains inside RBCs”
post splenectomy
“holly jolly got her spleen stolen!”

Question 20

Basophilic Stippling in RBCs are only seen in:

Answer 20

smear if stained!
blue spots
-=-lead poisoning

Question 21

Normal Hemoglobin

Answer 21

Women: 12-16
Men: 14-18

Question 22

MCHC is:

Answer 22

Mean Corpuscular Hemoglobin Concentration
REFLECTS THE COLOR of the RBC normal is 32-36.
Low: hypochromic-pale RBCs like IDA
Normal: normochromic
High: hyperchromic is rare

Question 23

MCH is:

Answer 23

reflects the avg WEIGHT of hemoglobin per RBC, rarely used

Question 24

Normal RDW is

Answer 24

<14.5%

Question 25

Thrombocytosis

Answer 25

Splenectomy.
Myeloproliferative dz and other CA.
Hemolytic Anemia
PV

Question 26

Thrombocytopenia

Answer 26

Acute leukemias
Aplastic anemia
ITP
TTP
DIC

Question 27

Normal Reticulocyte count is

Answer 27

0.5% - 1.5%