Catalase Pos. GPR- Bacillus Flashcards
List two catalyst negative gPR’s
Lactobacillus and Erysipelothrix
When I going to find gram-positive rods it’s good to know which bacteria tend to be much larger
Bacillus tend to be much larger
Blank are the only aerobic endospore farmers
Bacillus
How would one differentiate between wisteria and group B beta-hemolytic streptococci
Listeria is catalase positive, group B beta hemolytic streptococci are catalase negative
Name to gram-positive rods that are motile
Listeria and bacillus
On what media would you look for Hydrogen sulfide production
TSI
Anthrax, etiological agent…
Bacillus anthracis
Bacillus cereus is the etiological agent for…
Food poisoning
Describe what bacillus would look like under the microscope
Large purple box the rods
however note: older cells tend to stain gram-negative
Most of the species are blank and highly blank
Beta hemolytic, Motile
The most common route of infection with bacillus anthracis is…
From infected animal
The most common sign of anthrax
Esschar lesion
Anthrax is spread via blank
Endospores
Blank are essential for the virulence of anthrax
Siderophores and Iron heme scavengers
List three catalase positive GPR’s
Corynebacterium, Listeria, bacillus
2 virulence plasmids of anthrax
PXO1 and pXO2
Blank contains genes needed for synthesis of poly glutamic acid capsule
pXO2
Blank protects anthrax against phagocytic killing
pXO2
Blank contains genes encoding two anthrax toxins
pXO1
pXO1 consists of what three genes
PagA, lef, cya
Anthrax Genes PAG A
Protective antigen (PA)
Anthrax Genes Lef
Lethal factor (LF)
Anthrax genes CYA
Edema factor (EF)
Blank is a transcriptional activator of anthrax toxins
AtxA
Blank is a transcription repressor of anthrax toxins
PagR
The B subunit of anthrax toxins is the blank
PA (protective antigen)
The A subunit of anthrax edema toxin is blank factor which is a blank
Edema factor, a calmodulin dependent adenylate cyclase
The A subunit of anthrax lethal toxin is blank factor which is a blank
Lethal factor, a zinc metalloprotease
Anthrax lethal toxin causes…
Cell death
Anthrax Edema toxin causes…
Edema is surrounding tissue
Lethal toxin targets blank and blank
Cardiomiocytes and vascular smooth muscle cells
Edema toxin targets a blank in the blank
Hepatocytes in the liver
Bacillus cereus is The etiological agent of blank and blank
Ocular infections and food poisoning
Emetic
Short incubation period
Bacillus cereus diarrheal food poisoning is due to blank and or blank
Heat labile enterotoxin Nhe and HBL
Bacillus cereus emetic food poisoning is due to blank made by blank
Cereulide (ETE), cereulide synthetase (ces)
Bacillus cereus s layer binds…
ECM components
Bacillus cereus virulence factors are regulated by…
Global regulatory PlcR
Model GRP organism to study sporulation…
Bacillus subtilis
Bacillus anthracis has nonsense mutation in blank that don’t allow specific mutations found in bacillus cereus
PlcR
