cases Flashcards

0
Q

DIC

A

complex systemic thromboheorrhagic disorder that uses intravasclar fibrin, consumption of procoagulants and platelets

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1
Q

waterhouse-friderichsen syndrome

A

overwhelming bacterial infection common caused by Neisseria meningitidis septicemia

rapidly progresses to hypotensionand shock

DIC with widepsread purpura

bilateral adrenal hemorrhage because bacteria settle in small vessels

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2
Q

mechanism DIC

A

initiation of coagulation via endothelial injury/tissue damage

  • ->subsequent release of procoagulant material in the form of cytokines and tissue factors
  • ->platelet mediated fibrin formation
  • ->generalized bleeding–>hypperfusion, infarction, and end-organ damage
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3
Q

HSV can be vertically transmitted to infant before, during, orafter delivery

A

antenatal-5%
intra partum- passage through birth control- 75% asymptomatic
postnatal- cntact

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4
Q

antenatal

A

primary infection- transcient viremia occurs

findings are similar to TORCH infectins (microcephaly, micropthalamia, intracranial calcifications

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